Publikationen der AG Suchtforschung

Publikationen
Mehr als 100 Ver?ffentlichungen in peer-reviewed Journalen.
Ausgew?hlte Publikationen in den Arbeitsgebieten:

Genetische Grundlagen

1)?? ?Schmidt AW, …, Wodarz N, et al.?
Colocalization analysis of pancreas eQTLs with risk loci from alcoholic and novel non-alcoholic chronic pancreatitis GWAS suggests potential disease causing mechanisms.?
Pancreatology. 2022 May;22(4):449-456. doi: 10.1016/j.pan.2022.03.007. Epub 2022 Mar 11. PMID: 35331647
2)?? ?Munn-Chernoff MA,…, Wodarz N, et al. Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies.?Addict Biol. 2021 Jan;26(1):e12880. doi: 10.1111/adb.12880. Epub 2020 Feb 16.
3)?? ?Johnson EC, …, Psychiatric Genomics Consortium Substance Use Disorders Workgroup, Wodarz N, et al.?A large-scale genome-wide association study meta-analysis of cannabis use disorder. Lancet Psychiatry. 2020 Dec;7(12):1032-1045. doi: 10.1016/S2215-0366(20)30339-4. Epub 2020 Oct 20.?
4)?? ?Strnad P, …, Wodarz N, et al.?Heterozygous carriage of the alpha1-antitrypsin Pi*Z variant increases the risk to develop liver cirrhosis.?Gut. 2019 Jun;68(6):1099-1107. doi: 10.1136/gutjnl-2018-316228. Epub 2018 Aug 1.?[IF: 16.6]

5)?? ?Walters RK, …, Wodarz N, et al.?Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.?Nature Neurosci. 2018 Dec;21(12):1656-1669. doi: 10.1038/s41593-018-0275-1. Epub 2018 Nov 26. [IF 19.91]
6)?? ?Rosendahl J, …, Wodarz N et al.; all members of the PanEuropean Working group on ACP.?Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.?Gut. 2017 Jul 28. pii: gutjnl-2017-314454 [IF: 16.6]
7)?? ?Derikx MH, …., Wodarz N et al.?Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study.?Gut. 2015 Sep;64(9):1426-33 [IF: 13,3]

8)?? ?Stephan Buch1*, …., Norbert Wodarz9, et al.?A TWO-STAGE GENOME-WIDE ASSOCIATION STUDY CONFIRMS PNPLA3 AND IDENTIFIES TM6SF2 AND MBOAT7 AS RISK LOCI FOR ALCOHOL-RELATED CIRRHOSIS?Nature Genetics 2015 Dec;47(12):1443-8 [IF: 29.35]
9)?? ?Levey D, …, ?N Wodarz, et al.?Genetic Risk Prediction and Neurobiological Understanding of Alcoholism. Transl Psychiatry. 2014 May 20;4:e391. doi: 10.1038/tp.2014.29 [IF: 4,4 ]
10)?? ?Juraeva Dilafruz, …, Norbert Wodarz, et al.?XRCC5 as a Risk Gene for Alcohol Dependence: Evidence from a Genome-Wide Gene-Set Based Analysis and Follow-up Studies in Drosophila and Humans?Neuropsychopharmacology 2014: 1-11 [IF: 8,7]
11)?? ?Easton AC, …, Wodarz N, ?GESGA Consortium, et al.?αCaMKII autophosphorylation controls the establishment of alcohol drinking behavior.?Neuropsychopharmacology. 2013 Aug;38(9):1636-47 [IF: 8.68]
12)?? ?Gelernter J, …, Norbert Wodarz, ?et al.?Genomewide association study of alcohol dependence: Significant findings in African- and European-Americans including novel risk loci. Molecular Psychiatry 2014: 19:41-9 [IF: 15.05]?
13)?? ?Toni-Kim Clarke, Emma Dempster, Sophia J. Docherty , Sylvane Desrivieres, Anbarasu Lourdsamy, Norbert Wodarz, Moniker Ridinger, Wolfgang Maier Marcella Rietschel and Gunter Schumann?Multiple polymorphisms in genes of the adrenergic stress system confer vulnerability to alcohol abuse. ADDICTION BIOLOGY 2012; 17:202-8 [IF: 5.00]
14)?? ?Frank, Josef; Cichon, …., ?Wodarz, Norbert; et al.?Genome-Wide Significant Association between Alcohol Dependence and a Variant in the ADH Gene Cluster
ADDICTION BIOLOGY 2012; 17:171-180 [IF: 5.00]
15)?? ?Li Dong, …, Norbert Wodarz, et al.?The circadian rhythm gene Period1 is associated with psychosocial stress-induced alcohol drinking.?AMERICAN JOURNAL OF PSYCHIATRY 2011; 168: 1090-8 [IF: 12.5]
16)?? ?Felix Stickel1*, …, Norbert Wodarz6, et al.?Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in Caucasians
HEPATOLOGY. 2011 53(1):86-95 [IF: 10.9]
17)?? ?Preuss Ulrich; Monika Ridinger; Dan Rujescu; Jerzy Samochowiec; Christoph, Fehr; Friedrich Wurst; Gabriele Kolller; Brigitta Bondy; Norbert Wodarz; Debniak, Tomas; Anna Grzywacz; Michael Soyka; Peter Zill.?Association of ADH4 genetic variants with alcohol dependence risk and related phenotypes: results from a larger multicenter association study.?ADDICTION BIOLOGY 2011 Apr;16(2):323-33 [IF: 4,95]
18)?? ?Toni-Kim Clarke, Manfred Laucht, Monika Ridinger, Norbert Wodarz, ?Marcella Rietschel, Wolfgang Maier, Mark Lathrop, Anbarasu Lourdusamy, Ulrich S. Zimmermann, Sylvane Desrivieres & Gunter Schumann. KCNJ6 is associated with adult alcohol dependence and involved in gene x early life stress interactions in adolescent alcohol drinking.?NEUROPSYCHOPHARMACOLOGY 2011 May;36(6):1142-8. ?[IF: 6,99]
19)?? ?Desrivières Sylvane, Sergey P. Pronko, Anbarasu Lourdusamy, Francesca Ducci, Paula L. Hoffman, Norbert Wodarz, Monika Ridinger, Marcella Rietschel, Diana Zelenika, Mark Lathrop, Gunter Schumann, Boris Tabakoff.?Sex-specific role for adenylyl cyclase 7 in alcohol dependence.?BIOLOGICAL PSYCHIATRY 2011 69:1100-8. ?[IF: 8.9]
20)?? ?Falk Kiefer*, Stephanie H. Witt*, Josef Frank, Anne Richter, Jens Treutlein, Tagrid Lemenager, Markus M. N?then, Sven Cichon, Anil Batra, Michael Berner, Norbert Wodarz, Ulrich Zimmermann, Rainer Spanagel, Klaus Wiedemann, Michael Smolka, Andreas Heinz, Marcella Rietschel*, Karl Mann*?Involvement of the atrial natriuretic peptide transcription factor GATA4 in alcohol dependence, relapse risk, and treatment response to acamprosate.?PHARMACOGENOMICS JOURNAL ?2011; 11:368-74 [IF: 5,44]
21)?? ?UW Preuss, Ridinger M, Rujescu D, Fehr C, Koller G, Wodarz N, Soyka M, Wong WM, Zill P.?No association of alcohol dependence with Homer 1 and 2 SNPs and haplotypes.?AMERICAN JOURNAL OF MEDICAL GENETICS B NEUROPSYCHIATRIC GENETICS 2010: 153B(5):1102-9 [IF: 3,93]
22)?? ?Jens Treutlein*, Sven Cichon*, Monika Ridinger*, Norbert Wodarz, et al.?
Genome-wide association study of alcohol dependence.?ARCHIVES OF GENERAL PSYCHIATRY 2009: 66(7):773-784 [IF 16.1]
23)?? ?Erwin G?bele#, Marcus Mühlbauer#, Hartwig Paulo, Monika Johann , Christin Meltzer, Franz Leidl, Norbert Wodarz, Reiner Wiest, Jürgen Sch?lmerich, Claus Hellerbrand. Analysis of a MCP-1 gene polymorphism in patients with spontaneous bacterial peritonitis.?WORLD JOURNAL OF GASTROENTEROLOGY, 2009: 15(44):5558-62 [IF: 3.3]
24)?? ?Gunter Schumann; Monika Johann; …, Norbert Wodarz; et al.?Systematic Analysis of Glutamatergic Neurotransmission Genes in Alcohol Dependence and Adolescent Risky Drinking Behavior.?ARCHIVES OF GENERAL PSYCHIATRY 2008;65 826-838 [IF 16.1]
25)?? ?Johann M, Putzhammer A, Eichhammer P, Wodarz N.?Association of the -141C Del variant of the dopamine D2 receptor (DRD2) with positive family history and suicidality in German alcoholics.?AMERICAN JOURNAL OF MEDICAL GENETICS. 132B:46–49 (2005) [Impact: 2.4]

Take-Home Naloxon und Substitutionsgestützte Behandlung Opioidabh?ngiger

1)?? ?Norbert Wodarz, J?rg Wolstein, Oliver Pogarell, Heike Wodarz-von Essen?. Take-Home-Naloxon für Opioidabh?ngige: ein Beitrag zur Schadensminderung??Jahrbuch Sucht 2023, 209 – 232, Pabst Science Publishers
2)?? ?Wodarz-von Essen HJ, Wolstein J, Pogarell O, Wodarz N. Drogennotfallschulung Opioidabh?ngiger in Haft und Versorgung mit Take-Home Naloxon bei Haftentlassung: Machbarkeitsstudie aus dem bayerischen Modellprojekt [First Aid Training for Drug Overdose in Opioid Addicts and Provision of Take-Home Naloxone on Release from Prison: Feasibility Study from the Bavarian Model Project]. Gesundheitswesen. 2023 Jun;85(6):568-572. German. doi: 10.1055/a-1860-1048
3)?? ?Wodarz von Essen H., Pogarell O., Wolstein J., Wodarz N.?Take-home Naloxone for Trained Opioid Addicts - How Do They Deal with Overdose Emergencies | Take-Home-Naloxon für geschulte Opioidabh?ngige - Erfahrungen zum Umgang mit ?berdosierungsnotf?llen.?NOTARZT 2022; 38(03): 138-142
4)?? ?Zimmermann M., Hilgarth H., Ittner K.P., Wodarz N. The emergency pharmacological importance of nasally applied naloxone. [in German]?Notarzt 2020;36(6):317-319. doi:10.1055/a-1273-9536
5)?? ?Wodarz N., Wolstein J., Wodarz von Essen H, Pogarell O. Naloxon - Medical basics and international experience. [in German]?Sucht 2019;65(5):335-342. doi:10.1024/0939-5911/a000624
6)?? ?Weiss M, Gei?els?der K, Breuer M, Dechant M, Endres J, Stemmler M, Wodarz N. Behandlung opioidabh?ngiger Inhaftierter – Einstellungen und Behandlungspraxis des medizinischen Personals in bayerischen Justizvollzugsanstalten [Treatment of Opioid-dependent Inmates - Attitudes and Treatment Practice of medical Staff in Bavarian Prisons].?Gesundheitswesen. 2022 Dec;84(12):1107-1112. German. doi: 10.1055/a-1399-9286.
7)?? ?Pogarell O., Wodarz Von Essen H., Wodarz N. SARS-CoV-2 Pandemic and Addictive Disorders: Focus on Opioid Dependence and Opioid Maintenance Treatment-The Bavarian Experience. [in German]?Sucht 2020;66(5):271-277. doi:10.1024/0939-5911/a000679
8)?? ?Kunstmann W, Specka M, Wodarz N, Scherbaum N.?Scientific Rationale for the Directive on Opioid Substitution Treatment of the German Medical Association: A Summary. Gesundheitswesen. 2020 Nov;82(11):915-919. doi: 10.1055/a-1173-9588. Epub 2020 Jul 1.

ADHS

1)?? ?Philipsen A, …, Wodarz N; et al., ; Comparison of Methylphenidate and Psychotherapy in Adult ADHD Study (COMPAS) Consortium.?Effects of Group Psychotherapy, Individual Counseling, Methylphenidate, and Placebo in the Treatment of Adult Attention-Deficit/Hyperactivity Disorder: A Randomized Clinical Trial.
JAMA Psychiatry. 2015 Dec;72(12):1199-210. [IF: 13,23]
2)?? ?Ridinger M, Koenig S, Lange K, Wodarz N.?Bindungsstile und Alkoholabh?ngigkeit: Einfluss unsicherer Bindungsstile auf Ph?notypen der Alkoholabh?ngigkeit unter Berücksichtigung eines ADHS.?NERVENARZT, 2009: 80(7):827-32. [IF 0.8]
3)?? ?K Lange, Wodarz N, Laufk?tter R, Johann M.?Aufmerksamkeitsdefizit-Hyperaktivit?tssyndrom (ADHS) und Alkoholabh?ngigkeit: gibt es klinische Zusammenh?nge??PRAKTISCHE P?DIATRIE ?11: 387-392 (2005)
4)?? ?Johann M., G. Bobbe, A. Putzhammer, and N. Wodarz Comorbidity of alcohol dependence with attention-deficit hyperactivity disorder: Differences in phenotype with increased severity of the substance disorder, but not in genotype (Serotonin transporter, 5-HT2c receptor)?ALCOHOLISM: CLINICAL AND EXPERIMENTAL RESEARCH ?27:1527-1534 (2003) [Impact: 2.7]

Glücksspiel

1)?? ?H?rtl, S., Schr?der, S., Gartner, C., Wodarz, N. Beratung Angeh?riger pathologischer Glücksspieler/-innen: Status quo und Unterstützungsbedarf.?Suchttherapie 2023; 24(02): 73-81
2)?? ?Buchner UG, Koytek A, Fischer UC, Wodarz N, Wolstein J.?Psychometric Evaluation of the German Version of the Short Questionnaire for Family Members - Affected by Addiction SQFM-AA (Gambling)?Psychother Psychosom Med Psychol. 2016 Mar;66(3-04):155-62. [IF: 1.12]
3)?? ?Buchner UG, B Erbas, M Stürmer, M Arnold, N Wodarz, J Wolstein.?Inpatient treatment for pathological gamblers in Germany - setting, utilization and structure.
J Gambl Stud. 2015: 31(1):257-79 [IF: 2.0]
4)?? ?Buchner U, Arnold M, Koytek A, Gollrad T, Wodarz N Nicht nur Spieler brauchen Hilfe – Ergebnisse einer Pilotstudie zum Angeh?rigenprojekt ETAPPE?
PSYCHOTHERAPIE, PSYCHOSOMATIK UND MEDIZINISCHE PSYCHOLOGIE 2012; 62: 383 – 389 [IF: 0.9]
5)?? ?Buchner U, Koytek A, Arnold M, Gollrad T, Wodarz N.?Stabilisieren sich Entlastung und Stressreduktion bei Angeh?rigen pathologischer Glücksspieler nach der Teilnahme am psychoedukativen Training ETAPPE.?Zeitschrift für Gesundheitspsychologie 2013: 21: ?167 – 176. (IF: 0.32)
6)?? ?Buchner U, N. Wodarz.?Pathologisches Glücksspielen – aktueller Stand des Wissens
PSYCHOTHERAPIE, PSYCHOSOMATIK UND MEDIZINISCHE PSYCHOLOGIE 2011; 61: 341-346 [IF: 0.9]

Suchterkrankungen

1)?? ?Bonnet, Udo; Specka, Michael; Soyka, Michael; Alberti, Thomas; Bender, Stefan; Hilger, J?rg; Hillemacher, Thomas; Kuhlmann, Thomas; Kuhn, Jens; Lüdecke, Christel; Reimer, Jens; Schneider, Udo; Schroeder, Welf; Stuppe, Markus; Wiesbeck, Gerhard; Wodarz, Norbert; Scherbaum, Norbert
Weighing the benefits and harms of psychotropic and analgesic substances - A perspective of German addiction medicine experts.?Fortschr Neurol Psychiatr 2022; 90(01/02): 19-29
2)?? ?Kiefer F, Batra A, Petersen K, U, Ardern I, S, Tananska D, Bischof G, Funke W, Lindenmeyer J, Mueller S, Preuss U, W, Sch?fer M, Thomasius R, Veltrup C, Weissinger V, Wodarz N, Wurst F, M, Hoffmann S:?German Guidelines on Screening, Diagnosis, and Treatment of Alcohol Use Disorders: Update 2021.?Eur Addict Res 2022;28:309-322. doi: 10.1159/000522335
3)?? ?Lautenschlager F, Weiss M, Feuerer S, Wodarz N.??[Kratom - a short review for pain medicine].?Schmerz. 2022 Apr;36(2):128-134. doi: 10.1007/s00482-021-00588-9. Epub 2021 Sep 17. PMID: 34533652 Free PMC article. Review. German.?
4)?? ?Lautenschlager F., Huebner J., Steffling D., Ittner K.P., Wodarz N.?Kratom: What to look out for in case of intoxication?. [in German]?Notarzt 2021;37(1):9-11. doi:10.1055/a-1255-5130
5)?? ?Bonnet U, Specka M, Soyka M, Alberti T, Bender S, Grigoleit T, Hermle L, Hilger J, Hillemacher T, Kuhlmann T, Kuhn J, Luckhaus C, Lüdecke C, Reimer J, Schneider U, Schroeder W, Stuppe M, Wiesbeck GA, Wodarz N, McAnally H, Scherbaum N.?Ranking the Harm of Psychoactive Drugs Including Prescription Analgesics to Users and Others-A Perspective of German Addiction Medicine Experts.?Front Psychiatry. 2020 Oct 26;11:592199. doi: 10.3389/fpsyt.2020.592199
6)?? ?Wodarz N., Muehlig S., Thomasius R. Novel Psychoactive Substances - A comprehensive synopsis. [in German]?Sucht 2019;65(6):362-370. doi:10.1024/0939-5911/a000633
7)?? ?Wodarz Norbert1*, Anne Krampe-Scheidler2*, Michael Christ3, Heribert Fleischmann4, Winfried Looser5, Katharina Schoett6, Frank Vilsmeier7, Lydia Bothe2, Corinna Schaefer2 and Euphrosyne Gouzoulis-Mayfrank8. Evidence-based Guidelines for the Pharmacological Management of Acute Methamphetamine-related Disorders/Toxicity.?Pharmacopsychiatry. 2017 May;50(3):87-95 [IF: 1,5]
8)?? ?Hufnagel A, Frick U, Ridinger M, Wodarz N. Recovery from alcohol dependence: Do smoking indicators predict abstinence??Am J Addict. 2017 Jun;26(4):366-373. [IF: 1.87]
9)?? ?Gouzoulis-Mayfrank E, H?rtel-Petri R, Hamdorf W, Havemann-Reinecke U, Mühlig S, Wodarz N. Methamphetamine-Related Disorders.?Dtsch Arztebl Int. 2017 Jun 30;114(26):455-461. doi: 10.3238/arztebl.2017.0455.?
10)?? ?Mann K, E. Hoch, A. Batra, U. Bonnet, A. Günthner, G. Reymann, M. Soyka, N. Wodarz, M Sch?fer.?Leitlinienorientierte Behandlung alkoholbezogener St?rungen
Der Nervenarzt 2016 Jan;87(1):13-25. [IF: 0.8]
11)?? ?Karl Mann*, Tagrid Lemenager*, Sabine Hoffmann , Iris Reinhard, Derik Hermann, Anil Batra, Michael Berner, Norbert Wodarz, Andreas Heinz, Michael Smolka, Ulrich Zimmermann, , Falk Kiefer*, Stefan Wellek* and the PREDICT Study Team.?Results of a double-blind, placebo-controlled pharmacotherapy trial in alcoholism conducted in Germany and comparison with the US COMBINE study.?ADDICTION BIOLOGY 2013: 18(6):937-46 [IF: 5.00]

12)?? ?Mann K, Wellek S, Kr?mer R, Smolka M, Bergtholdt D, Kirchner B, Schr?der J, Ebert D, Berner M, Hagenbuch H, Kluge M, Richter B, Batra A, Deuschle M, Victor N, Mann K, Smolka M, Kiefer F, Gann H, Berner M, Schr?der J, Pantel J, Batra A, Wodarz N, Johann M, Hagenbuch H, Richter B, Kluge M.?Searching for responders to acamprosate and naltrexone in alcoholism treatment: rationale and design of the PREDICT study.
ALCOHOLISM: CLINICAL AND EXPERIMENTAL RESEARCH 2009: 33(4):674-83. [IF: 3.326]
13)?? ?Soyka M, Koller G, Schmidt P, Lesch OM, Leweke M, Fehr C, Gann H, Mann KF; Fleischhacker W, Ansoms G, De Nayer P, Van Dorpe W, Batel P, Danel P, Paille F, Peyron M, Reocreux Y, Vabret N, B?ning J, Bonnet U, Heuser I, Kurz M, L?hnert G, Richter G, Sch?fer M, Schmidt L, Von Keyserlingk H, Wodarz N, Daeppen JB, Gache JP.?Cannabinoid receptor 1 blocker rimonabant (SR 141716) for treatment of alcohol dependence: results from a placebo-controlled, double-blind trial.?JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY 2008 28(3):317-24. [IF 4.528]
14)?? ?Lange K, Wodarz N, Hajak G.?Abh?ngigkeitspotential der GABA-A-Rezeptor-agonistischen Nicht-Benzodiazepin-Hypnotika.?SUCHT 53: 201-213 (2007)
15)?? ?Koethe D, Juelicher A, Nolden BM, Braunwarth WD, Klosterk?tter J, Niklewski G, Wodarz N, Klatt J, Burtscheidt W, Gaebel W, Leweke FM.?Oxcarbazepine - efficacy and tolerability during treatment of alcohol withdrawal. A double-blind, randomized, placebo-controlled multicenter pilot study.?ALCOHOLISM: CLINICAL AND EXPERIMENTAL RESEARCH, 31: 1-7 (2007) [IF 2.933]
16)?? ?Eichhammer P, Johann M, Kharraz A, Binder H, Pittrow D, Wodarz N, Hajak G.
High-frequency repetitive transcranial magnetic stimulation decreases cigarette smoking.?JOURNAL OF CLINICAL PSYCHIATRY. 8:951-3 (2003) [Impact: 4.7]
17)?? ?Fleischmann H., N. Wodarz.?"Chronisch mehrfach beeintr?chtigt Alkoholabh?ngige" - Anwendbarkeit und psychometrische Aspekte eines Vorschlages zur operationalisierten Diagnostik.?SUCHT 45: 34-44 (1999)
18)?? ?Wodarz, N., G.A. Wiesbeck, H. Rommelspacher, P. Riederer, J. B?ning: Excretion of ?-carbolines Harman and Norharman in 24-hour urine of chronic alcoholics during withdrawal and controlled abstinence.?ALCOHOLISM: CLINICAL AND EXPERIMENTAL RESEARCH ?20: 706 - 710 (1996) [Impact: 2.7]
19)?? ?Wodarz, N., J.Fritze, J.Kornhuber, P.Riederer: 3H-Spiperone binding to human peripheral mononuclear cells: methodological aspects.?BIOLOGICAL PSYCHIATRY 31: 291-303 (1992) [Impact: 5.5]