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Please note that it is mandatory to state the source of funding in publications:
?Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), project number 387509280, SFB 1350“ .?

For publications related to the TRR 374, please specify ?Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), project number 509149993, TRR 374“ .

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2024

Schueler J, Kuenzel J, Thuesing A, Pion E, Behncke RY, Haegerling R, Fuchs D, Kraus A, Buchholz B, Huang B, Merhof D, Werner JM, Schmidt KM, Hackel C, Aung T, H?rteis S.
Ultra high frequency ultrasound enables real-time visualization of blood supply from chorioallantoic membrane to human autosomal dominant polycystic kidney tissue.
Sci Rep 14, 10063 (2024). doi.org/10.1038/s41598-024-60783-3
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Ousingsawat J, Centeio R, Reyne N, McCarron A, Cmielewski P, Schreiber R, diStefano G, R?mermann D, Seidler U, Donnelley M, Kunzelmann K.
Inhibition of mucus secretion by niclosamide and benzbromarone in airways and intestine.
Sci Rep. 2024 Jan 17;14(1):1464. doi: 10.1038/s41598-024-51397-w. PMID: 38233410; PMCID: PMC10794189.
PubMed

Ousingsawat J, Centeio R, Schreiber R, Kunzelmann K.
Niclosamide, but not ivermectin, inhibits anoctamin 1 and 6 and attenuates inflammation of the respiratory tract.
Pflugers Arch. 2024 Feb;476(2):211-227. doi: 10.1007/s00424-023-02878-w. Epub 2023 Nov 18. PMID: 37979051; PMCID: PMC10791962.
PubMed

Sandersfeld M, Büttner-Herold M, Ferrazzi F, Amann K, Benz K, Daniel C.
Macrophage subpopulations in pediatric patients with lupus nephritis and other inflammatory diseases affecting the kidney.
Arthritis Res Ther. 2024 Feb 8;26(1):46. doi: 10.1186/s13075-024-03281-1. PMID: 38331818; PMCID: PMC10851514.
PubMed

Sure F, Einsiedel J, Gmeiner P, Duchstein P, Zahn D, Korbmacher C, Ilyaskin AV.
The small molecule activator S3969 stimulates the epithelial sodium channel (ENaC) by interacting with a specific binding pocket in the channel's β-subunit.
J Biol Chem. 2024 Feb 22:105785. doi: 10.1016/j.jbc.2024.105785. Epub ahead of print. PMID: 38401845.
PubMed

Angeloni M, van Doeveren T, Lindner S, Volland P, Schmelmer J, Foersch S, Matek C, Stoehr R, Geppert CI, Heers H, Wach S, Taubert H, Sikic D, Wullich B, van Leenders GJ, Zaburdaev V, Eckstein M, Hartmann A, Boormans JL, Ferrazzi F, Bahlinger V.
A deep-learning workflow to predict upper tract urothelial carcinoma protein-based subtypes from H&E slides supporting the prioritization of patients for molecular testing.
J Pathol Clin Res. 2024 Mar;10(2):e12369. doi: 10.1002/2056-4538.12369. PMID: 38504364; PMCID: PMC10951050.
PubMed

Miyauchi H, Geisberger S, Luft FC, Wilck N, Stegbauer J, Wiig H, Dechend R, Jantsch J, Kleinewietfeld M, Kempa S, Müller DN.
Sodium as an Important Regulator of Immunometabolism.
Hypertension. 2024 Mar;81(3):426-435. doi: 10.1161/HYPERTENSIONAHA.123.19489. Epub 2023 Sep 7. PMID: 37675565; PMCID: PMC10863658.
PubMed

Skoczynski K, Kraus A, Daniel C, Büttner-Herold M, Amann K, Schiffer M, Hermann K, Herrnberger-Eimer L, Tamm ER, Buchholz B.
The extracellular matrix protein fibronectin promotes metanephric kidney development.
Pflugers Arch. 2024 Apr 2. doi: 10.1007/s00424-024-02954-9. Epub ahead of print. PMID: 38563997.
PubMed

K?sters P, Cazorla-Vázquez S, Krüger R, Daniel C, Vonbrunn E, Amann K, Engel FB.
Adhesion G Protein-Coupled Receptor Gpr126 (Adgrg6) Expression Profiling in Diseased Mouse, Rat, and Human Kidneys.
Cells. 2024 May 18;13(10):874. doi: 10.3390/cells13100874. PMID: 38786096; PMCID: PMC11119830.
PubMed

Schlieben LD, Carta MG, Moskalev EA, St?hr R, Metzler M, Besend?rfer M, Meidenbauer N, Semrau S, Janka R, Grützmann R, Wiemann S, Hartmann A, Agaimy A, Haller F, Ferrazzi F.
Machine Learning-Supported Diagnosis of Small Blue Round Cell Sarcomas Using Targeted RNA Sequencing.
J Mol Diagn. 2024 May;26(5):387-398. doi: 10.1016/j.jmoldx.2024.02.002. Epub 2024 Feb 21. PMID: 38395409.
PubMed

Schreiber R, Ousingsawat J, Kunzelmann K.
The anoctamins: Structure and function.
Cell Calcium. 2024 Jun;120:102885. doi: 10.1016/j.ceca.2024.102885. Epub 2024 Apr 15. PMID: 38642428.
PubMed

Kunzelmann K, Ousingsawat J, Schreiber R. VSI:
The anoctamins: Structure and function: "Intracellular" anoctamins.
Cell Calcium. 2024 Jun;120:102888. doi: 10.1016/j.ceca.2024.102888. Epub 2024 Apr 17. PMID: 38657371.
PubMed

Ousingsawat J, Talbi K, Gómez-Martín H, Koy A, Fernández-Jaén A, Tekgül H, Serdaro?lu E, Schreiber R, Ortigoza-Escobar JD, Kunzelmann K.
Broadening the clinical spectrum: molecular mechanisms and new phenotypes of ANO3-dystonia.
Brain. 2024 Jun 3;147(6):1982-1995. doi: 10.1093/brain/awad412. PMID: 38079528.
PubMed

Kraus A, Skoczynski K, Br?tsch M, Burzlaff N, Leipziger J, Schiffer M, Büttner-Herold M, Buchholz B.
P2Y2R and Cyst Growth in Polycystic Kidney Disease.
J Am Soc Nephrol. 2024 Jun 7. doi: 10.1681/ASN.0000000000000416. Epub ahead of print. PMID: 38848134.
Pubmed

Vonbrunn E, Daniel C.
Die Komplementkaskade in der Nierenpathologie [The complement cascade in renal pathology].
Pathologie (Heidelb). 2024 Jul;45(4):246-253. German. doi: 10.1007/s00292-024-01320-x. Epub 2024 Apr 5. PMID: 38578365.
PubMed

Büttner-Herold M, Amann K, Velden J.
Nephropathologie infekti?ser Erkrankungen [Nephropathology of infectious disease].
Pathologie (Heidelb). 2024 Jul;45(4):254-260. German. doi: 10.1007/s00292-024-01322-9. Epub 2024 Apr 10. PMID: 38598098.
PubMed

Wopperer FJ, Olinger E, Wiesener A, Broeker KAE, Knaup KX, Schaefer JT, Galiano M, Schneider K, Schiffer M; Genomics England Research Consortium; Büttner-Herold M, Reis A, Schmieder R, Pasutto F, Hilgers KF, Poglitsch M, Ziegler C, Shoemaker R, Sayer JA, Wiesener MS.
Progressive Kidney Failure by Angiotensinogen Inactivation in the Germline.
Hypertension. 2024 Sep;81(9):1857-1868. doi: 10.1161/HYPERTENSIONAHA.124.22806. Epub 2024 Jul 15. PMID: 39005223.
PubMed

Ousingsawat J, Schreiber R, Kunzelmann K.
Functional Interdependence of Anoctamins May Influence Conclusions from Overexpression Studies.
Int J Mol Sci. 2024 Sep 17;25(18):9998. doi: 10.3390/ijms25189998. PMID: 39337485; PMCID: PMC11432102.
PubMed

Sure F, Afonso S, Essigke D, Schmidt P, Kalo MZ, Nesterov V, Ki?ler A, Bertog M, Rinke R, Wittmann S, Broeker KAE, Gramberg T, Artunc F, Korbmacher C, Ilyaskin AV.

Transmembrane Serine Protease 2 and Proteolytic Activation of the Epithelial Sodium Channel in Mouse Kidney.
J Am Soc Nephrol. 2024 Oct 23. doi: 10.1681/ASN.0000000521. Epub ahead of print. PMID: 39441656.
PubMed

Herold JM, Wiegrebe S, Nano J, Jung B, Gorski M, Thorand B, Koenig W, Zeller T, Zimmermann ME, Burkhardt R, Banas B, Küchenhoff H, Stark KJ, Peters A, B?ger CA, Heid IM.
Population-based reference values for kidney function and kidney function decline in 25- to 95-year-old Germans without and with diabetes.
Kidney Int. 2024 Oct;106(4):699-711. doi: 10.1016/j.kint.2024.06.024. Epub 2024 Jul 29. PMID: 39084259.
PubMed

Jensen M, Heinl ES, Federlein A, Schwartz U, Lund L, Madsen K, Jensen BL, Schweda F.
Identification of natriuretic peptide receptor A-related gene expression signatures in podocytes in vivo reveals baseline control of protective pathways.
Am J Physiol Renal Physiol. 2024 Nov 1;327(5):F806-F821. doi: 10.1152/ajprenal.00394.2023. Epub 2024 Sep 19. PMID: 39298549.
PubMed

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2025

Ousingsawat J, Talbi K, Gómez-Martín H, Koy A, Fernández-Jaén A, Tekgül H, Serdaro?lu E, Ortigoza-Escobar JD, Schreiber R, Kunzelmann K.
Dystonia caused by ANO3 variants is due to attenuated Ca2+ influx by ORAI1.
BMC Med. 2025 Jan 7;23(1):12. doi: 10.1186/s12916-024-03839-5. PMID: 39773217; PMCID: PMC11707858.
PubMed

Schreiber R, Ousingsawat J, Kunzelmann K.
Anoctamin 9 determines Ca2+ signals during activation of T-lymphocytes.
Front Immunol. 2025 Mar 26;16:1562871. doi: 10.3389/fimmu.2025.1562871. PMID: 40207216; PMCID: PMC11979140.
PubMed

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2023

2023

Vonbrunn E, Büttner-Herold M, Amann K, Daniel C.
Complement Inhibition in Kidney Transplantation: Where Are We Now?
BioDrugs. 2023 Jan;37(1):5-19. doi: 10.1007/s40259-022-00567-1. Epub 2022 Dec 13. PMID: 36512315; PMCID: PMC9836999.
PubMed

Schanz M, Kimmel M, Alscher MD, Amann K, Daniel C.
TIMP-2 and IGFBP7 in human kidney biopsies in renal disease.
Clin Kidney J. 2023 Jan 16;16(9):1434-1446. doi: 10.1093/ckj/sfad010. PMID: 37664566; PMCID: PMC10468751.
PubMed

Kraus A, Lüdke A, Teschemacher B, Skoczynski K, Buchholz B.
In?vitro cyst puncture and injury-induced tubule formation using renal epithelial cells.
STAR Protoc. 2023 Jan 19;4(1):101874. doi: 10.1016/j.xpro.2022.101874. Epub ahead of print. PMID: 36856763; PMCID: PMC10037192.
PubMed

Schreiber R, Talbi K, Ousingsawat J, Kunzelmann K.
A TMEM16J variant leads to dysregulated cytosolic calcium which may lead to renal disease.
FASEB J. 2023 Jan;37(1):e22683. doi: 10.1096/fj.202200968R. PMID: 36520003.
PubMed

C?rte-Real BF, Hamad I, Arroyo Hornero R, Geisberger S, Roels J, Van Zeebroeck L, Dyczko A, van Gisbergen MW, Kurniawan H, Wagner A, Yosef N, Weiss SNY, Schmetterer KG, Schr?der A, Krampert L, Haase S, Bartolomaeus H, Hellings N, Saeys Y, Dubois LJ, Brenner D, Kempa S, Hafler DA, Stegbauer J, Linker RA, Jantsch J, Müller DN, Kleinewietfeld M.
Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs.
Cell Metab. 2023 Feb 7;35(2):299-315.e8. doi: 10.1016/j.cmet.2023.01.009. PMID: 36754020.
PubMed

Dagorn PG, Buchholz B, Kraus A, Batchuluun B, Bange H, Blockken L, Steinberg GR, Moller DE, Hallakou-Bozec S.
A novel direct adenosine monophosphate kinase activator ameliorates disease progression in preclinical models of Autosomal Dominant Polycystic Kidney Disease.
Kidney Int. 2023 Feb 18:S0085-2538(23)00122-9. doi: 10.1016/j.kint.2023.01.026. Epub ahead of print. PMID: 36804411.
PubMed

Donhauser FJ, Zimmermann ME, Steinkirchner AB, Wiegrebe S, Dietl A, Brandl C, Burkhardt R, Gessner A, Schweda F, Bergler T, Sch?ffner E, B?ger CA, Kronenberg F, Luchner A, Stark KJ, Heid IM.
Cardiovascular Risk Factor Control in 70- to 95-Year-Old Individuals: Cross-Sectional Results from the Population-Based AugUR Study.
J Clin Med. 2023 Mar 7;12(6):2102. doi: 10.3390/jcm12062102. PMID: 36983106; PMCID: PMC10054695.
PubMed

Heinl ES, Broeker KA, Lehrmann C, Heydn R, Krieger K, Ortmaier K, Tauber P, Schweda F.
Localization of natriuretic peptide receptors A, B, and C in healthy and diseased mouse kidneys.
Pflugers Arch. 2023 Mar;475(3):343-360. doi: 10.1007/s00424-022-02774-9. Epub 2022 Dec 8. PMID: 36480070; PMCID: PMC9908653.
PubMed

Sinha F, Federlein A, Biesold A, Schwarzfischer M, Krieger K, Schweda F, Tauber P.
Empagliflozin increases kidney weight due to increased cell size in the proximal tubule S3 segment and the collecting duct.
Front Pharmacol. 2023 Mar 23;14:1118358. doi: 10.3389/fphar.2023.1118358. PMID: 37033639; PMCID: PMC10076569.
PubMed

Grampp S, Krüger R, Lauer V, Uebel S, Knaup KX, Naas J, H?ffken V, Weide T, Schiffer M, Naas S, Sch?del J.
Hypoxia hits APOL1 in the kidney.
Kidney Int. 2023 Apr 23:S0085-2538(23)00266-1. doi: 10.1016/j.kint.2023.03.035. Epub ahead of print. PMID: 37098381.
PubMed

Grampp S, Kraus A, Skoczynski K, Schiffer M, Krüger R, Naas S, Sch?del J, Buchholz B.
Hypoxia induces polycystin-1 expression in the renal epithelium.
R. Soc. OpenSci. 2023 10: 220992.
https://doi.org/10.1098/rsos.220992

Centeio R, Cabrita I, Schreiber R, Kunzelmann K.
TMEM16A/F support exocytosis but do not inhibit Notch-mediated goblet cell metaplasia of BCi-NS1.1 human airway epithelium.
Front Physiol. 2023 May 9;14:1157704. doi: 10.3389/fphys.2023.1157704. PMID: 37234411; PMCID: PMC10206426.
PubMed

Herold JM, Nano J, Gorski M, Winkler TW, Stanzick KJ, Zimmermann ME, Brandl C, Peters A, Koenig W, Burkhardt R, Gessner A, Heid IM, Gieger C, Stark KJ.
Polygenic scores for estimated glomerular filtration rate in a population of general adults and elderly - comparative results from the KORA and AugUR study.
BMC Genom Data. 2023 May 25;24(1):28. doi: 10.1186/s12863-023-01130-9. PMID: 37231333; PMCID: PMC10210501.
PubMed

Naas S, Krüger R, Knaup KX, Naas J, Grampp S, Schiffer M, Wiesener M, Sch?del J.
Hypoxia controls expression of kidney-pathogenic MUC1 variants.
Life Sci Alliance. 2023 Jun 14;6(9):e202302078. doi: 10.26508/lsa.202302078. PMID: 37316299; PMCID: PMC10267510.
PubMed

B?hme R, Daniel C, Ferrazzi F, Angeloni M, Ekici AB, Winkler TH, Hilgers KF, Wellmann U, Voll RE, Amann K.
Cardiovascular changes in the NZB/W F1 mouse model of lupus nephritis.
Front Cardiovasc Med. 2023 Jul 24;10:1182193. doi: 10.3389/fcvm.2023.1182193. PMID: 37554366; PMCID: PMC10405627.
PubMed

Cazorla-Vázquez S, K?sters P, Bertz S, Pfister F, Daniel C, Dedden M, Zundler S, Jobst-Schwan T, Amann K, Engel FB.
Adhesion GPCR Gpr126 (Adgrg6) Expression Profiling in Zebrafish, Mouse, and Human Kidney.
Cells. 2023 Aug 2;12(15):1988. doi: 10.3390/cells12151988. PMID: 37566066; PMCID: PMC10417176.
PubMed

Kunzelmann K, Ousingsawat J, Kraus A, Park JH, Marquardt T, Schreiber R, Buchholz B.
Pathogenic Relationships in Cystic Fibrosis and Renal Diseases: CFTR, SLC26A9 and Anoctamins.
Int J Mol Sci. 2023 Aug 26;24(17):13278. doi: 10.3390/ijms241713278. PMID: 37686084; PMCID: PMC10487509.
PubMed

Talbi K, Ousingsawat J, Centeio R, Schreiber R, Kunzelmann K.
KCNE1 does not shift TMEM16A from a Ca2+ dependent to a voltage dependent Cl- channel and is not expressed in renal proximal tubule.
Pflugers Arch. 2023 Aug;475(8):995-1007. doi: 10.1007/s00424-023-02829-5. Epub 2023 Jul 13. PMID: 37442855; PMCID: PMC10359377.
PubMed

Naas S, Schiffer M, Sch?del J.
Hypoxia and renal fibrosis.
Am J Physiol Cell Physiol. 2023 Oct 1;325(4):C999-C1016. doi: 10.1152/ajpcell.00201.2023. Epub 2023 Sep 4. PMID: 37661918.
PubMed

Wahida A, Schmaderer C, Büttner-Herold M, Branca C, Donakonda S, Haberfellner F, Torrez C, Schmitz J, Schulze T, Seibt T, ?llinger R, Engleitner T, Haller B, Steiger K, Günthner R, Lorenz G, Yabal M, Bachmann Q, Braunisch MC, Moog P, Matevossian E, A?falg V, Thorban S, Renders L, Sp?th MR, Müller RU, Stippel DL, Weichert W, Slotta-Huspenina J, von Vietinghoff S, Viklicky O, Green DR, Rad R, Amann K, Linkermann A, Br?sen JH, Heemann U, Kemmner S.
High RIPK3 expression is associated with a higher risk of early kidney transplant failure.
iScience. 2023 Sep 17;26(10):107879. doi: 10.1016/j.isci.2023.107879. PMID: 37868627; PMCID: PMC10585402.
PubMed

Sinha F, Schweda F, Maier LS, Wagner S.
Impact of Impaired Kidney Function on Arrhythmia-Promoting Cardiac Ion Channel Regulation.
International Journal of Molecular Sciences. 2023; 24(18):14198.
https://doi.org/10.3390/ijms241814198

Stanzick KJ, Stark KJ, Gorski M, Sch?del J, Krüger R, Kronenberg F, Warth R, Heid IM, Winkler TW.
KidneyGPS: a user-friendly web application to help prioritize kidney function genes and variants based on evidence from genome-wide association studies.
BMC Bioinformatics. 2023 Sep 21;24(1):355. doi: 10.1186/s12859-023-05472-0.
Pubmed

Meindl K, Issler N, Afonso S, Cebrian-Serrano A, Müller K, Sterner C, Othmen H, Tegtmeier I, Witzgall R, Klootwijk E, Davies B, Kleta R, Warth R.
A missense mutation in Ehd1 associated with defective spermatogenesis and male infertility.
Front Cell Dev Biol. 2023 Oct 12;11:1240558. doi: 10.3389/fcell.2023.1240558.
Pubmed

Gaupp C, Schmid B, Tripal P, Edwards A, Daniel C, Zimmermann S, Goppelt-Struebe M, Willam C, Rosen S, Schley G.
Reconfiguration and loss of peritubular capillaries in chronic kidney disease.
Sci Rep. 2023 Nov 11;13(1):19660. doi: 10.1038/s41598-023-46146-4. PMID: 37952029; PMCID: PMC10640592.
PubMed

Ousingsawat J, Talbi K, Gómez-Martín H, Koy A, Fernández-Jaén A, Tekgül H, Serdaro?lu E, Schreiber R, Ortigoza-Escobar JD, Kunzelmann K.
Broadening the clinical spectrum: molecular mechanisms and new phenotypes of ANO3-dystonia.
Brain. 2023 Dec 11:awad412. doi: 10.1093/brain/awad412. Epub ahead of print. PMID: 38079528.
PubMed

Kunzelmann K, Centeio R, Ousingsawat J, Talbi K, Seidler U, Schreiber R.
SLC26A9 in airways and intestine: secretion or absorption?
Channels (Austin). 2023 Dec;17(1):2186434. doi: 10.1080/19336950.2023.2186434. PMID: 36866602; PMCID: PMC9988340.
PubMed

Krampert L, Ossner T, Schr?der A, Schatz V, Jantsch J.
Simultaneous Increases in Intracellular Sodium and Tonicity Boost Antimicrobial Activity of Macrophages.
Cells. 2023 Dec 11;12(24):2816. doi: 10.3390/cells12242816. PMID: 38132136; PMCID: PMC10741518.
PubMed

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2022

2022????????????

Fuchs MAA, Schrankl J, Leupold C, Wagner C, Kurtz A, Broeker K.
Intact prostaglandin signaling through EP2 and EP4 receptors in stromal progenitor cells is required for normal development of the renal cortex in mice.
Am J Physiol Renal Physiol. 2022 Jan 17. doi: 10.1152/ajprenal.00414.2021. Epub ahead of print. PMID: 35037469.
PubMed

W?rner S, Bohnert BN, W?rn M, Xiao M, Janessa A, Birkenfeld AL, Amann K, Daniel C, Artunc F.
Renal effects of the serine protease inhibitor aprotinin in healthy conscious mice.
Acta Pharmacol Sin. 2022 Jan;43(1):111-120. doi: 10.1038/s41401-021-00628-1. Epub 2021 Mar 23. PMID: 33758357; PMCID: PMC8724274.
PubMed

Niederreiter J, Eck C, Ries T, Hartmann A, M?rkl B, Büttner-Herold M, Amann K, Daniel C.
Complement Activation via the Lectin and Alternative Pathway in Patients With Severe COVID-19. Front Immunol. 2022 Feb 2;13:835156. doi: 10.3389/fimmu.2022.835156. PMID: 35237273; PMCID: PMC8884149.
PubMed

Arzt M, Drzymalski MA, Ripfel S, Meindl S, Biedermann A, Durczok M, Keller K, Mustroph J, Katz S, Tafelmeier M, Lebek S, Fl?rchinger B, Camboni D, Wittmann S, Backs J, Schmid C, Maier LS, Wagner S.
Enhanced Cardiac CaMKII Oxidation and CaMKII-Dependent SR Ca Leak in Patients with Sleep-Disordered Breathing.
Antioxidants (Basel). 2022 Feb 8;11(2):331. doi: 10.3390/antiox11020331. PMID: 35204213; PMCID: PMC8868143.
PubMed

Issler N, Afonso S, Weissman I, Jordan K, Cebrian-Serrano A, Meindl K, Dahlke E, Tziridis K, Yan G, Robles-López JM, Tabernero L, Patel V, Kesselheim A, Klootwijk ED, Stanescu HC, Dumitriu S, Iancu D, Tekman M, Mozere M, Jaureguiberry G, Outtandy P, Russell C, Forst AL, Sterner C, Heinl ES, Othmen H, Tegtmeier I, Reichold M, Schiessl IM, Limm K, Oefner P, Witzgall R, Fu L, Theilig F, Schilling A, Shuster Biton E, Kalfon L, Fedida A, Arnon-Sheleg E, Ben Izhak O, Magen D, Anikster Y, Schulze H, Ziegler C, Lowe M, Davies B, B?ckenhauer D, Kleta R, Falik Zaccai TC, Warth R.
A Founder Mutation in EHD1 Presents with Tubular Proteinuria and Deafness.
J Am Soc Nephrol. 2022 Feb 11: epub ahead of print. doi: 10.1681/ASN.2021101312.
Pubmed
Editorial

Wester M, Pec J, Lebek S, Fisser C, Debl K, Hamer O, Poschenrieder F, Buchner S, Maier LS, Arzt M, Wagner S.
Sleep-Disordered Breathing Is Associated With Reduced Left Atrial Strain Measured by Cardiac Magnetic Resonance Imaging in Patients After Acute Myocardial Infarction.
Front Med (Lausanne). 2022 Feb 16;9:759361. doi: 10.3389/fmed.2022.759361. PMID: 35252229; PMCID: PMC8888827.
PubMed

Broeker KAE, Fuchs MAA, Schrankl J, Lehrmann C, Schley G, Todorov VT, Hugo C, Wagner C, Kurtz A.
Prolyl-4-hydroxylases 2 and 3 control erythropoietin production in renin-expressing cells of mouse kidneys.
J Physiol. 2022 Feb;600(3):671-694. doi: 10.1113/JP282615. Epub 2021 Dec 27. PMID: 34863041.
PubMed

Baumgartner A, Reichelt-Wurm S, Gronwald W, Samol C, Schr?der JA, Fellner C, Holler K, Steege A, Putz FJ, Oefner PJ, Banas B, Banas MC.
Assessment of Physiological Rat Kidney Ageing-Implications for the Evaluation of Allograft Quality Prior to Renal Transplantation.
Metabolites. 2022 Feb 8;12(2):162. doi: 10.3390/metabo12020162. PMID: 35208236; PMCID: PMC8875225.
PubMed

Protze J, Naas S, Krüger R, St?hr C, Kraus A, Grampp S, Wiesener M, Schiffer M, Hartmann A, Wullich B, Sch?del J.
The renal cancer risk allele at 14q24.2 activates a novel hypoxia-inducible transcription factor-binding enhancer of DPF3 expression.
J Biol Chem. 2022 Mar;298(3):101699. doi: 10.1016/j.jbc.2022.101699. Epub 2022 Feb 8. PMID: 35148991; PMCID: PMC8897700.
PubMed

Kjaergaard AD, Teumer A, Witte DR, Stanzick KJ, Winkler TW, Burgess S, Ellervik C.
Obesity and Kidney Function: A Two-Sample Mendelian Randomization Study.
Clin Chem. 2022 Mar 4;68(3):461-472. doi: 10.1093/clinchem/hvab249. PMID: 34922334.
PubMed

Lo J, Forst AL, Warth R, Zdebik AA.
EAST/SeSAME Syndrome and Beyond: The Spectrum of Kir4.1- and Kir5.1-Associated Channelopathies.
Front Physiol. 2022 Mar 15;13:852674. doi: 10.3389/fphys.2022.852674.
Pubmed

Vonbrunn E, Angeloni M, Büttner-Herold M, Müller-Deile J, Heller K, Bleich E, S?llner S, Amann K, Ferrazzi F, Daniel C.
Can Gene Expression Analysis in Zero-Time Biopsies Predict Kidney Transplant Rejection?
Front Med (Lausanne). 2022 Mar 30;9:793744. doi: 10.3389/fmed.2022.793744. PMID: 35433772; PMCID: PMC9005644.
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Baier MJ, Wagner S, Hupf J, Evert K, Evert M, Sossalla S, Jungbauer C, Maier LS, Neef S, Mustroph J.
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Infection. 2022 Apr;50(2):547-552. doi: 10.1007/s15010-021-01722-6. Epub 2021 Oct 20. PMID: 34669163; PMCID: PMC8527292.
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Sure F, Bertog M, Afonso S, Diakov A, Rinke R, Madej MG, Wittmann S, Gramberg T, Korbmacher C, Ilyaskin AV.
Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel's γ-subunit.
J Biol Chem. 2022 Apr 30:102004. doi: 10.1016/j.jbc.2022.102004 . Epub ahead of print. PMID: 35504352 .
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Scholz JK, Kraus A, Lüder D, Skoczynski K, Schiffer M, Grampp S, Sch?del J, Buchholz B.
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iScience. 2022 May 5;25(6):104359. doi: 10.1016/j.isci.2022.104359. PMID: 35620436; PMCID: PMC9127160.
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Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.
Commun Biol. 2022 Jun 13;5(1):580. doi: 10.1038/s42003-022-03448-z. PMID: 35697829; PMCID: PMC9192715.
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Heinz V, Güler G, Leone V, Madej MG, Maksimov S, G?rtner RM, Rudi O, Hamdi F, Kastritis PL, M?ntele W, Kr?mer R, Forrest LR, Perez C, Ziegler C.
Osmotic stress response in BetP: How lipids and K+ team up to overcome downregulation.
bioRxiv 2022.06.02.493408; doi:

Bichlmayer EM, Mahl L, Hesse L, Pion E, Haller V, Moehwald A, Hackl C, Werner JM, Schlitt HJ, Schwarz S, Kainz P, Brochhausen C, Groeger C, Steger F, K?lbl O, Daniel C, Amann K, Kraus A, Buchholz B, Aung T, Haerteis S.
A 3D In Vivo Model for Studying Human Renal Cystic Tissue and Mouse Kidney Slices. Cells. 2022 Jul 22;11(15):2269. doi: 10.3390/cells11152269. PMID: 35892566; PMCID: PMC9330914.
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Moulin S, Thomas A, Wagner S, Arzt M, Dubouchaud H, Lamarche F, Bouyon S, Vial G, Godin-Ribuot D, Pépin JL, Arnaud C, Belaidi E.
Intermittent Hypoxia-Induced Cardiomyocyte Death Is Mediated by HIF-1 Dependent MAM Disruption.
Antioxidants (Basel). 2022 Jul 27;11(8):1462. doi: 10.3390/antiox11081462. PMID: 36009181; PMCID: PMC9405320.
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Diakov A, Nesterov V, Dahlmann A, Korbmacher C.
Two adjacent phosphorylation sites in the C-terminus of the channel's α-subunit have opposing effects on epithelial sodium channel (ENaC) activity.
Pflugers Arch. 2022 Jul;474(7):681-697. doi: 10.1007/s00424-022-02693-9. Epub 2022 May 8. Erratum in: Pflugers Arch. 2022 Jun 9;: PMID: 35525869; PMCID: PMC9192390.
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Wopperer FJ, Knaup KX, Stanzick KJ, Schneider K, Jobst-Schwan T, Ekici AB, Uebe S, Wenzel A, Schliep S, Schürfeld C, Seitz R, Bernhardt W, G?del M, Wiesener A, Popp B, Stark KJ, Gr?ne HJ, Friedrich B, Wei? M, Basic-Jukic N, Schiffer M, Schr?ppel B, Huettel B, Beck BB; Genomics England Research Consortium, Sayer JA, Ziegler C, Büttner-Herold M, Amann K, Heid IM, Reis A, Pasutto F, Wiesener MS.
Diverse molecular causes of unsolved autosomal dominant tubulointerstitial kidney diseases.
Kidney Int. 2022 Aug;102(2):405-420. doi: 10.1016/j.kint.2022.04.031. Epub 2022 May 26. PMID: 35643372.
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Hermann K, Seibold S, Skoczynski K, Buchholz B, Tamm ER, Herrnberger-Eimer L.
Fibronectin deficiency in newborn mice leads to cyst formation in the kidney

Hegner P, Drzymalski M, Biedermann A, Memmel B, Durczok M, Wester M, Floerchinger B, Provaznik Z, Schmid C, Zausig Y, Maier LS, Wagner S.
SAR296968, a Novel Selective Na+/Ca2+ Exchanger Inhibitor, Improves Ca2+ Handling and Contractile Function in Human Atrial Cardiomyocytes.
Biomedicines. 2022 Aug 9;10(8):1932. doi: 10.3390/biomedicines10081932. PMID: 36009478; PMCID: PMC9406204.
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Lebek S, Hegner P, Hultsch R, Rohde J, Rupprecht L, Schmid C, Sossalla S, Maier LS, Arzt M, Wagner S.
Nav1.8 Dysregulates Na and Ca Leading to Arrhythmias in Patients with Sleep-disordered Breathing.
Am J Respir Crit Care Med. 2022 Aug 9. doi: 10.1164/rccm.202205-0981LE. Epub ahead of print. PMID: 35944144.
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Olinger E, Schaeffer C, Kidd K, Elhassan EAE, Cheng Y, Dufour I, Schiano G, Mabillard H, Pasqualetto E, Hofmann P, Fuster DG, Kistler AD, Wilson IJ, Kmoch S, Raymond L, Robert T; Genomics England Research Consortium, Eckardt KU, Bleyer AJ Sr, K?ttgen A, Conlon PJ, Wiesener M, Sayer JA, Rampoldi L, Devuyst O.
An intermediate-effect size variant in UMOD confers risk for chronic kidney disease.
Proc Natl Acad Sci U S A. 2022 Aug 16;119(33):e2114734119. doi: 10.1073/pnas.2114734119. Epub 2022 Aug 10. PMID: 35947615; PMCID: PMC9388113.
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Pearce D, Manis AD, Nesterov V, Korbmacher C.
Regulation of distal tubule sodium transport: mechanisms and roles in homeostasis and pathophysiology.
Pflugers Arch. 2022 Aug;474(8):869-884. doi: 10.1007/s00424-022-02732-5. Epub 2022 Jul 27. PMID: 35895103; PMCID: PMC9338908.
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Gorski M, Rasheed H, Teumer A, Thomas LF, Graham SE, Sveinbjornsson G, Winkler TW, Günther F, Stark KJ, Chai JF, Tayo BO, Wuttke M, Li Y, Tin A, Ahluwalia TS, ?rnl?v J, ?svold BO, Bakker SJL, Banas B, Bansal N, Biggs ML, Biino G, B?hnke M, Boerwinkle E, Bottinger EP, Brenner H, Brumpton B, Carroll RJ, Chaker L, Chalmers J, Chee ML, Chee ML, Cheng CY, Chu AY, Ciullo M, Cocca M, Cook JP, Coresh J, Cusi D, de Borst MH, Degenhardt F, Eckardt KU, Endlich K, Evans MK, Feitosa MF, Franke A, Freitag-Wolf S, Fuchsberger C, Gampawar P, Gansevoort RT, Ghanbari M, Ghasemi S, Giedraitis V, Gieger C, Gudbjartsson DF, Hallan S, Hamet P, Hishida A, Ho K, Hofer E, Holleczek B, Holm H, Hoppmann A, Horn K, Hutri-K?h?nen N, Hveem K, Hwang SJ, Ikram MA, Josyula NS, Jung B, K?h?nen M, Karabegovi? I, Khor CC, Koenig W, Kramer H, Kr?mer BK, Kühnel B, Kuusisto J, Laakso M, Lange LA, Lehtim?ki T, Li M, Lieb W; Lifelines Cohort Study, Lind L, Lindgren CM, Loos RJF, Lukas MA, Lyytik?inen LP, Mahajan A, Matias-Garcia PR, Meisinger C, Meitinger T, Melander O, Milaneschi Y, Mishra PP, Mononen N, Morris AP, Mychaleckyj JC, Nadkarni GN, Naito M, Nakatochi M, Nalls MA, Nauck M, Nikus K, Ning B, Nolte IM, Nutile T, O'Donoghue ML, O'Connell J, Olafsson I, Orho-Melander M, Parsa A, Pendergrass SA, Penninx BWJH, Pirastu M, Preuss MH, Psaty BM, Raffield LM, Raitakari OT, Rheinberger M, Rice KM, Rizzi F, Rosenkranz AR, Rossing P, Rotter JI, Ruggiero D, Ryan KA, Sabanayagam C, Salvi E, Schmidt H, Schmidt R, Scholz M, Sch?ttker B, Schulz CA, Sedaghat S, Shaffer CM, Sieber KB, Sim X, Sims M, Snieder H, Stanzick KJ, Thorsteinsdottir U, Stocker H, Strauch K, Stringham HM, Sulem P, Szymczak S, Taylor KD, Thio CHL, Tremblay J, Vaccargiu S, van der Harst P, van der Most PJ, Verweij N, V?lker U, Wakai K, Waldenberger M, Wallentin L, Wallner S, Wang J, Waterworth DM, White HD, Willer CJ, Wong TY, Woodward M, Yang Q, Yerges-Armstrong LM, Zimmermann M, Zonderman AB, Bergler T, Stefansson K, B?ger CA, Pattaro C, K?ttgen A, Kronenberg F, Heid IM.
Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies.
Kidney Int. 2022 Sep;102(3):624-639. doi: 10.1016/j.kint.2022.05.021. Epub 2022 Jun 16. PMID: 35716955.
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Popp B, Ekici AB, Knaup KX, Schneider K, Uebe S, Park J, Bafna V, Meiselbach H, Eckardt KU, Schiffer M, Reis A, Kraus C, Wiesener M.
Prevalence of hereditary tubulointerstitial kidney diseases in the German Chronic Kidney Disease study.
Eur J Hum Genet. 2022 Sep 13. doi: 10.1038/s41431-022-01177-9. Epub ahead of print. PMID: 36100708.
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Schreiber R, Cabrita I, Kunzelmann K.
Paneth Cell Secretion in vivo Requires Expression of Tmem16a and Tmem16f.
Gastro Hep Advances 2022; Vol 1, Issue 6:1088-1098, ISSN 2772-5723, doi.org/10.1016/j.gastha.2022.08.002
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Fuchs MAA, Schrankl J, Wagner C, Daniel C, Kurtz A, Broeker KA.
Localization and characterization of Proenkephalin-A as a potential biomarker for kidney disease in murine and human kidneys.
Biomarkers. 2022 Nov 10:1-15. doi: 10.1080/1354750X.2022.2146196. Epub ahead of print. PMID: 36354355.
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Daniel C, Enghard P, Ratnatunga N, Wijetunge S, Wazil AWM, Zwiener C, Barth JAC, Chandrajith R, Klewer M, Eckhardt KU, Amann K, Freund P, Premarathne S, Pushpakumara WDRN, Nanayakkara N.
Early Ultrastructural Changes in Biopsies From Patients With Symptomatic CKD of Uncertain Etiology.
Kidney Int Rep. 2022 Dec 31;8(3):642-657. doi: 10.1016/j.ekir.2022.12.022. PMID: 36938087; PMCID: PMC10014386.
Pubmed

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2021

2021

Cabrita I, Benedetto R, Wanitchakool P, Lerias J, Centeio R, Ousingsawat J, Schreiber R, Kunzelmann K.
TMEM16A Mediates Mucus Production in Human Airway Epithelial Cells.
Am J Respir Cell Mol Biol. 2021 Jan;64(1):50-58. doi: 10.1165/rcmb.2019-0442OC. PMID: 33026825.
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Benz K, Ferrazzi F, Galiano M, Sauerstein K, Vonbrunn E, Daniel C, Büttner-Herold M, Amann K.
Relevance of glomerular C4d deposition in pediatric patients with Henoch-Sch?nlein Purpura compared to IgA nephritis.
J Nephropathol. 2021;10(2):e16.DOI: 10.34172/jnp.2021.16.
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Pfister F, Vonbrunn E, Ries T, J?ck HM, ?berla K, Lochnit G, Sheriff A, Herrmann M, Büttner-Herold M, Amann K, Daniel C.
Complement Activation in Kidneys of Patients With COVID-19.
Front Immunol. 2021 Jan 29;11:594849. doi: 10.3389/fimmu.2020.594849. PMID: 33584662; PMCID: PMC7878379.
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Amann K, Boor P, Wiech T, Singh J, Vonbrunn E, Kn?ll A, Hermann M, Büttner-Herold M, Daniel C, Hartmann A.
COVID-19-Auswirkungen auf?die?Niere [COVID-19 effects on the kidney].
Pathologe. 2021 Feb 1:1–5. German. doi: 10.1007/s00292-020-00899-1. Epub ahead of print. PMID: 33527157; PMCID: PMC7849614.
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Tafelmeier M, Luft L, Zistler E, Floerchinger B, Camboni D, Creutzenberg M, Zeman F, Schmid C, Maier LS, Wagner S, Arzt M.
Central Sleep Apnea Predicts Pulmonary Complications After Cardiac Surgery.
Chest. 2021 Feb;159(2):798-809. doi: 10.1016/j.chest.2020.07.080. Epub 2020 Aug 13. PMID: 32798522.
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Schmid F, Grigo C, Büttner-Herold M, von H?rsten S, Amann K, Daniel C.
CD161a-positive natural killer (NK) cells and α-smooth muscle actin-positive myofibroblasts were upregulated by extrarenal DPP4 in a rat model of acute renal rejection.
Diabetes Res Clin Pract. 2021 Feb 4:108691. doi: 10.1016/j.diabres.2021.108691. Epub ahead of print. PMID: 33549675.
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Ilyaskin AV, Korbmacher C, Diakov A.
Inhibition of the epithelial sodium channel (ENaC) by connexin 30 involves stimulation of clathrin-mediated endocytosis.
J Biol Chem. 2021 Feb 9:100404. doi: 10.1016/j.jbc.2021.100404. Epub ahead of print. PMID: 33577799.
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Schrankl J, Fuchs M, Broeker K, Daniel C, Kurtz A, Wagner C.
Localization of Angiotensin II Type 1 receptor gene expression in rodent and human kidneys.
Am J Physiol Renal Physiol. 2021 Feb 22. doi: 10.1152/ajprenal.00550.2020. Epub ahead of print. PMID: 33615887.
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Essigke D, Ilyaskin AV, W?rn M, Bohnert BN, Xiao M, Daniel C, Amann K, Birkenfeld AL, Szabo R, Bugge TH, Korbmacher C, Artunc F.
Zymogen-locked mutant prostasin (Prss8) leads to incomplete proteolytic activation of the epithelial sodium channel (ENaC) and severely compromises triamterene tolerance in mice.
Acta Physiol (Oxf). 2021 Mar 1:e13640. doi: 10.1111/apha.13640. Epub ahead of print. PMID: 33650216.
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Fuchs MAA, Broeker KAE, Schrankl J, Burzlaff N, Willam C, Wagner C, Kurtz A.
Inhibition of transforming growth factor β1 signaling in resident interstitial cells attenuates profibrotic gene expression and preserves erythropoietin production during experimental kidney fibrosis in mice.
Kidney Int. 2021 Mar 8:S0085-2538(21)00278-7. doi: 10.1016/j.kint.2021.02.035. Epub ahead of print. PMID: 33705825.
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Park JH, Ousingsawat J, Cabrita I, Bettels RE, Gro?e-Onnebrink J, Schmalstieg C, Biskup S, Reunert J, Rust S, Schreiber R, Kunzelmann K, Marquardt T.
TMEM16A deficiency: a potentially fatal neonatal disease resulting from impaired chloride currents.
J Med Genet. 2021 Apr;58(4):247-253. doi: 10.1136/jmedgenet-2020-106978. Epub 2020 Jun 2. PMID: 32487539.
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Vonbrunn E, Serikova S, Daniel C, Amann K, Sch?del J, Buchholz B, Ferrazzi F, Heller K, Apel H, Büttner-Herold M.
Significance of Glomerular Immune Reactivity in Time Zero Biopsies for Allograft Survival Beyond IgA.
Front Med (Lausanne). 2021 Apr 6;8:656840. doi: 10.3389/fmed.2021.656840. PMID: 33889588; PMCID: PMC8057301.
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Ziegler V, Fremter K, Helmchen J, Witzgall R, Castrop H.
Mesangial cells regulate the single nephron GFR and preserve the integrity of the glomerular filtration barrier: An intravital multiphoton microscopy study.
Acta Physiol (Oxf). 2021 Apr;231(4):e13592. doi: 10.1111/apha.13592. Epub 2021 Mar 11. PMID: 33269519.
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Mustroph J, Sag CM, B?hr F, Schmidtmann AL, Gupta SN, Dietz A, Islam MMT, Lücht C, Beuthner BE, Pabel S, Baier MJ, El-Armouche A, Sossalla S, Anderson ME, M?llmann J, Lehrke M, Marx N, Mohler PJ, Bers DM, Uns?ld B, He T, Dewenter M, Backs J, Maier LS, Wagner S.
Loss of CASK Accelerates Heart Failure Development.
Circ Res. 2021 Apr 16;128(8):1139-1155. doi: 10.1161/CIRCRESAHA.120.318170. Epub 2021 Feb 17. PMID: 33593074; PMCID: PMC8049978.
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Cabrita I, Talbi K, Kunzelmann K, Schreiber R.
Loss of PKD1 and PKD2 share common effects on intracellular Ca2+ signaling.
Cell Calcium. 2021 Apr 24;97:102413. doi: 10.1016/j.ceca.2021.102413. Epub ahead of print. PMID: 33915319.
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Geisberger S, Bartolomaeus H, Neubert P, Willebrand R, Zasada C, Bartolomaeus T, McParland V, Swinnen D, Geuzens A, Maifeld A, Krampert L, Vogl M, M?hler A, Wilck N, Marko L, Tilic E, Forslund SK, Binger KJ, Stegbauer J, Dechend R, Kleinewietfeld M, Jantsch J, Kempa S, Müller DN.
Salt Transiently Inhibits Mitochondrial Energetics in Mononuclear Phagocytes.
Circulation. 2021 Apr 28. doi: 10.1161/CIRCULATIONAHA.120.052788. Epub ahead of print. PMID: 33906377.
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Centeio R, Ousingsawat J, Schreiber R, Kunzelmann K.
CLCA1 Regulates Airway Mucus Production and Ion Secretion Through TMEM16A.
Int J Mol Sci. 2021 May 12;22(10):5133. doi: 10.3390/ijms22105133. PMID: 34066250; PMCID: PMC8151571.
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Lebek S, Hegner P, Tafelmeier M, Rupprecht L, Schmid C, Maier LS, Arzt M, Wagner S.
Female Patients With Sleep-Disordered Breathing Display More Frequently Heart Failure With Preserved Ejection Fraction.
Front Med (Lausanne). 2021 May 28;8:675987. doi: 10.3389/fmed.2021.675987. PMID: 34124106; PMCID: PMC8192825.
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Steines L, Poth H, Schuster A, Amann K, Banas B, Bergler T.
Disruption of Tfh:B Cell Interactions Prevents Antibody-Mediated Rejection in a Kidney Transplant Model in Rats: Impact of Calcineurin Inhibitor Dose.
Front Immunol. 2021 May 31;12:657894. doi: 10.3389/fimmu.2021.657894. PMID: 34135891; PMCID: PMC8201497.
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Schlingmann KP, Renigunta A, Hoorn EJ, Forst AL, Renigunta V, Atanasov V, Mahendran S, Barakat TS, Gillion V, Godefroid N, Brooks AS, Lugtenberg D, Lake J, Debaix H, Rudin C, Knebelmann B, Tellier S, Rousset-Rouvière C, Viering D, deBaaij JHF, Weber S, Palygin O, Staruschenko A, Kleta R, Houillier P, Bockenhauer D, Devuyst O, Vargas-Poussou R, Warth R, Zdebik AA, Konrad M.
Defects in KCNJ16 Cause a Novel Tubulopathy with Hypokalemia, Salt Wasting, Disturbed Acid-Base Homeostasis, and Sensorineural Deafness.
J Am Soc Nephrol. 2021 Jun 1;32(6):1498-1512.
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Jobin K, Müller DN, Jantsch J, Kurts C.
Sodium and its manifold impact on our immune system.
Trends Immunol. 2021 Jun;42(6):469-479. doi: 10.1016/j.it.2021.04.002. Epub 2021 May 4. PMID: 33962888.
PubMed

Fischer LM, Fichte LA, Büttner-Herold M, Ferrazzi F, Amann K, Benz K, Daniel C.
Complement in Renal Disease as a Potential Contributor to Arterial Hypertension.
Kidney Blood Press Res. 2021;46(3):362-376. doi: 10.1159/000515823. Epub 2021 Jun 2. PMID: 34077925.
PubMed

Talbi K, Cabrita I, Schreiber R, Kunzelmann K.
Gender-Dependent Phenotype in Polycystic Kidney Disease Is Determined by Differential Intracellular Ca2+ Signals.
Int J Mol Sci. 2021 Jun 2;22(11):6019. doi: 10.3390/ijms22116019. PMID: 34199520; PMCID: PMC8199720.
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Berg P, Svendsen SL, Sorensen MV, Schreiber R, Kunzelmann K, Leipziger J.
The molecular mechanism of CFTR- and secretin-dependent renal bicarbonate excretion.
Physiol. 2021 Jun;599(12):3003-3011. doi: 10.1113/JP281285. Epub 2021 May 29. PMID: 33963548.
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Bach C, Knaup KX, Herrmann M, Krumbiegel M, Pfister F, Büttner-Herold M, Steffen M, Zecher D, Lopau K, Schneider K, Dieterle A, Amann K, Reis A, Schiffer M, Spriewald BM, Wiesener MS.
A noninvasive diagnostic approach to retrospective donor HLA typing in kidney transplant patients using urine.
Transpl Int. 2021 Jul;34(7):1226-1238. doi: 10.1111/tri.13893. Epub 2021 Jun 16. PMID: 33904183.
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H?ckl M, Tauber P, Schweda F, Zacharias HU, Altenbuchinger M, Oefner PJ, Gronwald W.
An R-Package for the Deconvolution and Integration of 1D NMR Data: MetaboDecon1D. Metabolites. 2021 Jul 13;11(7):452. doi: 10.3390/metabo11070452. PMID: 34357346; PMCID: PMC8305572.
PubMed

Stanzick KJ, Li Y, Schlosser P, Gorski M, Wuttke M, Thomas LF, Rasheed H, Rowan BX, Graham SE, Vanderweff BR, Patil SB; VA Million Veteran Program, Robinson-Cohen C, Gaziano JM, O'Donnell CJ, Willer CJ, Hallan S, ?svold BO, Gessner A, Hung AM, Pattaro C, K?ttgen A, Stark KJ, Heid IM, Winkler TW.
Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals.
Nat Commun. 2021 Jul 16;12(1):4350. doi: 10.1038/s41467-021-24491-0. PMID: 34272381; PMCID: PMC8285412.
PubMed

Forst AL, Reichold M, Kleta R, Warth R.
Distinct Mitochondrial Pathologies Caused by Mutations of the Proximal Tubular Enzymes EHHADH and GATM.
Front Physiol. 2021 Jul 19;12:715485.
Pubmed

Tonnus W, Meyer C, Steinebach C, Belavgeni A, von M?ssenhausen A, Gonzalez NZ, Maremonti F, Gembardt F, Himmerkus N, Latk M, Locke S, Marschner J, Li W, Short S, Doll S, Ingold I, Proneth B, Daniel C, Kabgani N, Kramann R, Motika S, Hergenrother PJ, Bornstein SR, Hugo C, Becker JU, Amann K, Anders HJ, Kreisel D, Pratt D, Gütschow M, Conrad M, Linkermann A.
Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury.
Nat Commun. 2021 Jul 20;12(1):4402. doi: 10.1038/s41467-021-24712-6. PMID: 34285231; PMCID: PMC8292346.
PubMed

Zacharias HU, Altenbuchinger M, Schultheiss UT, Raffler J, Kotsis F, Ghasemi S, Ali I, Kollerits B, Metzger M, Steinbrenner I, Sekula P, Massy ZA, Combe C, Kalra PA, Kronenberg F, Stengel B, Eckardt KU, K?ttgen A, Schmid M, Gronwald W, Oefner PJ; GCKD Investigators.
A Predictive Model for Progression of CKD to Kidney Failure Based on Routine Laboratory Tests.
Am J Kidney Dis. 2021 Jul 20:S0272-6386(21)00729-0. doi: 10.1053/j.ajkd.2021.05.018. Epub ahead of print. PMID: 34298143.
Pubmed