Publications

2017

Tamm ER, Dowling JE. Astrocytes and glaucomatous neurodegeneration. Exp Eye Res. (Pubmed)

Kugler M,?Schlecht A,?Fuchshofer R,?Schmitt SI,?Kleiter I,?Aigner L,?Tamm ER,?Braunger BM. (2017)? SMAD7 deficiency stimulates Müller progenitor cell proliferation during the development of the mammalian retina. Histochem Cell Biol. (Pubmed)

Stowell C,?Burgoyne CF,?Tamm ER,?Ethier CR;?Lasker/IRRF Initiative on Astrocytes and Glaucomatous Neurodegeneration Participants. (2017)? Biomechanical aspects of axonal damage in glaucoma: A brief review. Exp Eye Res.,S0014-4835(17)30056-8. (Pubmed)

2016

Elliott MH, Ashpole NE, Gu X, Herrnberger L, McClellan ME, Griffith GL, Reagan AM, Boyce TM, Tanito M, Tamm ER, Stamer WD. (2016) Caveolin-1 modulates intraocular pressure: implications for caveolae mechanoprotection in glaucoma. Sci Rep.; 6:37127. (Pubmed)

Koch MA, Rosenhammer B, Paper W, Volz C, Braunger BM, Hausberger J, J?gle H, Tamm ER. (2016) Mutated olfactomedin 1 in the interphotoreceptor matrix of the mouse retina causes functional deficits and vulnerability to light damage. Histochem Cell Biol. (Pubmed)

Ohlmann A, Scholz M, Koch M, Tamm ER. (2016) Epithelial-mesenchymal transition of the retinal pigment epithelium causes choriocapillaris atrophy. Histochem Cell Biol.; 146(6):769-780. (Pubmed)

Zeilbeck LF, Müller BB, Leopold SA, Senturk B, Langmann T, Tamm ER, Ohlmann A. (2016) Norrin mediates angiogenic properties via the induction of insulin-like growth factor-1. Exp Eye Res.;145:317-26. (Pubmed)

2015

Hennig R, Ohlmann A, Staffel J, Pollinger K, Haunberger A, Breunig M, Schweda F, Tamm ER, Goepferich A. (2015) Multivalent nanoparticles bind the retinal and choroidal vasculature. J Control Release. 2015 Oct 19;220(Pt A):265-274. (PubMed)

Tamm ER, Braunger BM, Fuchshofer R. (2015) Intraocular Pressure and the Mechanisms Involved in Resistance of the Aqueous Humor Flow in the Trabecular Meshwork Outflow Pathways. Prog Mol Biol Transl Sci. 2015;134:301-14. (PubMed)

Kugler M, Schlecht A, Fuchshofer R, Kleiter I, Aigner L, Tamm ER, Braunger BM. (2015) Heterozygous modulation of TGF-β signaling does not influence Müller glia cell reactivity or proliferation following NMDA-induced damage. Histochem Cell Biol. 2015 Nov;144(5):443-55. (PubMed)

Ohana R, Weiman-Kelman B, Raviv S, Tamm ER, Pasmanik-Chor M, Rinon A, Netanely D, Shamir R, Solomon AS, Ashery-Padan R. (2015) MicroRNAs are essential for differentiation of the retinal pigmented epithelium and maturation of adjacent photoreceptors. Development. 2015 Jul 15;142(14):2487-98. (PubMed)

Braunger BM, Fuchshofer R, Tamm ER. (2015) The aqueous humor outflow pathways in glaucoma: A unifying concept of disease mechanisms and causative treatment. Eur J Pharm Biopharm. 2015 Sep;95(Pt B):173-81. (PubMed)

Braunger BM, Leimbeck SV, Schlecht A, Volz C, J?gle H, Tamm ER. Deletion of ocular transforming growth factor β signaling mimics essential characteristics of diabetic retinopathy. Am J Pathol. 2015 Jun;185(6):1749-68. (PubMed)

Kuespert S, Junglas B, Braunger BM, Tamm ER, Fuchshofer R. (2015).???????????????????????? The regulation of connective tissue growth factor expression influences the viability of human trabecular meshwork cells. J Cell Mol Med. 2015 May;19(5):1010-20. (PubMed)?

2014

Koch MA, Rosenhammer B, Koschade SE, Braunger BM, Volz C, J?gle H, Tamm ER (2014). Myocilin modulates programmed cell death during retinal development. Exp Eye Res. May 15;125C:41-52. (PubMed)

Zeilbeck LF, Müller B, Knobloch V, Tamm ER, Ohlmann A (2014). Differential angiogenic properties of lithium chloride in vitro and in vivo. PLoS One 9(4):e95546. (PubMed)

Forkwa TK, Tamm ER, Ohlmann A (2014). Ambiguous role of glucocorticoids on survival of retinal neurons. Adv. Exp. Med. Biol. 801:365-71. (PubMed)

Seitz R, Tamm ER. (2014) Müller cells and microglia of the mouse eye react throughout the entire retina in response to the procedure of an intravitreal injection. Adv Exp Med Biol.; 801:347-53. (PubMed)

Sippl C, Tamm ER (2014). What is the Nature of the RGC-5 Cell Line? Adv Exp Med Biol. 801:145-54. (PubMed)

Strau? O, Müller C, Reichhart N, Tamm ER, Gomez NM (2014). The role of bestrophin-1 in intracellular ca(2+) signaling. Adv Exp Med Biol. 801:113-9. (PubMed)

Braunger BM, Demmer C, Tamm ER (2014). Programmed cell death during retinal development of the mouse eye. Adv Exp Med Biol. 801:9-13. (PubMed)

Karlstetter M, Sorusch N, Caramoy A, Dannhausen K, Aslanidis A, Fauser S, Boesl MR, Nagel-Wolfrum K, Tamm ER, J?gle H, Stoehr H, Wolfrum U, Langmann T (2014). Disruption of the Retinitis Pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration. Hum Mol Genet. May 15. (PubMed)

Fuchshofer R, Kuespert S, Junglas B, Tamm ER (2014). The prostaglandin f2α analog fluprostenol attenuates the fibrotic effects of connective tissue growth factor on human trabecular meshwork cells. J Ocul Pharmacol Ther. Mar-Apr;30(2-3):237-45. (PubMed)

Forkwa TK, Neumann ID, Tamm ER, Ohlmann A, Reber SO (2014). Short-term psychosocial stress protects photoreceptors from damage via corticosterone-mediated activation of the AKT pathway. Exp Neurol. Feb;252:28-36. (PubMed)

2013

Seitz R, Tamm ER (2013). N-methyl-D-aspartate (NMDA)-mediated excitotoxic damage: A mouse model of acute retinal ganglion cell damage. Methods Mol. Biol. 935, 99-109. (PubMed)

Tamm ER (2013). [Functional morphology of the outflow pathways of aqueous humor and their changes in open angle glaucoma]. [Article in German] Ophthalmologe. Nov;110(11):1026-35. (PubMed)

Hornig J, Fr?b F, Vogl MR, Hermans-Borgmeyer I, Tamm ER, Wegner M (2013). The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes.PLoS Genet. 2013 Oct;9(10):e1003907. doi: 10.1371/journal.pgen.1003907. Epub 2013 Oct 31. (PubMed)

Mirza M, Volz C, Karlstetter M, Langiu M, Somogyi A, Ruonala MO, Tamm ER, J?gle H, Langmann T (2013). Progressive Retinal Degeneration and Glial Activation in the CLN6 (nclf) Mouse Model of Neuronal Ceroid Lipofuscinosis: A Beneficial Effect of DHA and Curcumin Supplementation. PLoS One. 2013 Oct 4;8(10):e75963. (PubMed)

Clark A, Tamm ER, Al-Ubaidi MR, Hollyfield JG (2013). On the use of immortalized ocular cell lines in vision research: the unfortunate story of RGC-5. Exp Eye Res.; 116:433. (PubMed)

Tamm ER, Grehn F, Pfeiffer N (2013). Neuroprotection in glaucoma. Cell Tissue Res. Aug;353(2):201-3. (PubMed)

Braunger BM, Pielmeier S, Demmer C, Landstorfer V, Kawall D, Abramov N, Leibinger M, Kleiter I, Fischer D, J?gle H, Tamm ER (2013). TGF-β signaling protects retinal neurons from programmed cell death during the development of the mammalian eye. J Neurosci. Aug 28;33(35):14246-58. (PubMed)

Seitz R, Ohlmann A, Tamm ER (2013). The role of Müller glia and microglia in glaucoma. Cell Tissue Res. Aug;353(2):339-45. (PubMed)

Tamm ER, Schmetterer L, Grehn F (2013). Status and perspectives of neuroprotective therapies in glaucoma: the European Glaucoma Society White Paper. Cell Tissue Res. Aug;353(2):347-54. (PubMed)

Gómez NM, Tamm ER, Strauβ O. (2013) Role of bestrophin-1 in store-operated calcium entry in retinal pigment epithelium. Pflugers Arch. Apr;465(4):481-95. (PubMed)

Pollinger K, Hennig R, Ohlmann A, Fuchshofer R, Wenzel R, Breunig M, Tessmar J, Tamm ER, Goepferich A (2013) Ligand-functionalized nanoparticles target endothelial cells in retinal capillaries after systemic application. Proc. Natl. Acad. Sci. 110:6115-20 (PubMed)

Seitz R., Tamm E.R. (2013). N-methyl-D-aspartate (NMDA)-mediated excitotoxic damage: A mouse model of acute retinal ganglion cell damage. Methods Mol. Biol. 935, 99-109. (PubMed)

2012

Braunger B.M., Ohlmann A., Koch M., Tanimoto N., Volz C., Yang Y., B?sl M.R., Cvekl A., J?gle H., Seeliger M.W., Tamm ER. (2012). Constitutive overexpression of Norrin activates Wnt/β-catenin and endothelin-2 signaling to protect photoreceptors from light damage. Neurobiol. Dis. 50, 1-12. (PubMed)

Herrnberger L., Ebner K., Junglas B., Tamm ER. (2012). The role of plasmalemma vesicle-associated protein (PLVAP) in endothelial cells of Schlemm's canal and ocular capillaries. Exp. Eye Res. 105, 27-33 (PubMed)

Tamm ER, Ohlmann A. (2012) Entwicklung des menschlichen Auges. [Development of the human eye]. Ophthalmologe, 109, 911-28. (PubMed)

Herrnberger L., Seitz R., Kuespert S. B?sl M.R., Fuchshofer R., Tamm ER. (2012) Lack of endothelial diaphragms in fenestrae and caveolae of mutant Plvap-deficient mice. Histochem Cell Biol. 138,709-24. (PubMed)

Junglas B, Kuespert S, Seleem AA, Struller T, Ullmann S, B?sl M, Bosserhoff A, K?stler J, Wagner R, Tamm ER, Fuchshofer R. Connective tissue growth factor causes glaucoma by modifying the actin cytoskeleton of the trabecular meshwork. Am J Pathol.; 180(6):2386-403. (PubMed)

Ohlmann A, Tamm ER. (2012).
Norrin: Molecular and functional properties of an angiogenic and neuroprotective growth factor. Prog Retin Eye Res., 31, 243-257. (PubMed)

Braunger BM, Tamm ER. (2012). The different functions of norrin. Adv. Exp. Med. Biol., 723, 679-683. (PubMed)

Fr?b F, Bremer M, Finzsch M, Kichko T, Reeh P, Tamm ER, Charnay P, Wegner M (2012). Establishment of myelinating schwann cells and barrier integrity between central and peripheral nervous systems depend on Sox10. Glia, 60, 806-819. (PubMed)

Fuchshofer R, Tamm ER. (2012).The role of TGF-β in the pathogenesis of primary open-angle glaucoma. Cell Tissue Res., 347, 279-290. (PubMed)

2011

Sippl C, Bosserhoff AK, Fischer D, Tamm ER. (2011) Depletion of optineurin in RGC-5 cells derived from retinal neurons causes apoptosis and reduces the secretion of neuro-trophins. Exp Eye Res. (PubMed)

Fuchshofer R, Ullmann S, Zeilbeck LF, Baumann M. Junglas B, Tamm ER. (2011)
Connective tissue growth factor modulates podocyte actin cytoskeleton and extracellular matrix synthesis and is induced in podocytes upon injury. Histochem Cell Biol. (PubMed)

Ohlmann A, Merkl R, Tamm ER. (2011). Focus on Molecules: Norrin. Exp. Eye Res. (PubMed)

Tamm ER. (2011). Entwicklung des Kammerwinkels und kongenitales Glaukom [Development of the iridocorneal angle and congenital glaucoma]. Ophthalmologe, 108, 610-617. (PubMed)

Kritzenberger M, Junglas B, Framme C, Helbig H, Gabel VP, Fuchshofer R, Tamm ER, Hillenkamp J. (2011). Different collagen types define two types of idiopathic epiretinal membranes. Histopathology, ;58, 953-965. (PubMed)

Gallenberger M, Meinel DM, Kroeber M, Wegner M, Milkereit P, Boesl MR, Tamm ER. (2011) Lack of WDR36 leads to preimplantation embryonic lethality in mice and delays the formation of small subunit ribosomal RNA in human cells in vitro.
Hum Mol Genet.; 20(3):422-35. (PubMed)

Bohr D, Koch M., Kritzenberger M, Fuchshofer R, Tamm ER. (2011) Increased expression of olfactomedin-1 and myocilin in podocytes during puromycin aminonucleoside nephrosis. Nephrology Dialysis Transplantation; 26(1):83-92 (PubMed)

2010

Kroeber M, Davis N, Holzmann S, Kritzenberger M, Shelah-Goraly M, Ofri R, Ashery-Padan R, Tamm ER. (2010) Reduced Expression of Pax6 in Lens and Cornea of Mutant Mice Leads to Failure of Chamber Angle Development and Juvenile Glaucoma. Hum Mol Genet. (PubMed)

Finzsch M, Schreiner S, Kichko T, Reeh P, Tamm ER, B?sl MR, Meijer D, Wegner M. (2010) Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage. J Cell Biol.; 189(4):701-12. (PubMed)

Seitz R, Hackl S, Seibuchner T, Tamm ER, Ohlmann A. (2010) Norrin mediates neuroprotective effects on retinal ganglion cells via activation of the Wnt/beta-catenin signaling pathway and the induction of neuroprotective growth factors in Muller cells. J Neurosci.; 30(17):5998-6010. (PubMed)

Ohlmann A, Seitz R, Braunger B, Seitz D, B?sl MR, Tamm ER. (2010). Norrin promotes vascular regrowth after oxygen-induced retinal vessel loss and suppresses retinopathy in mice. J Neurosci.; 30(1):183-93.(PubMed)

2009

Konz DD, Flügel-Koch C, Ohlmann A, Tamm ER. (2009) Myocilin in the trabecular meshwork of eyes with primary open-angle glaucoma. Graefes Arch Clin Exp Ophthalmol.; 247(12):1643-9. (PubMed)

Goldwich A, Scholz M, Tamm ER. (2009). Myocilin promotes substrate adhesion, spreading and formation of focal contacts in podocytes and mesangial cells. Histochem Cell Biol.; 131(2):167-80. (PubMed)

Wolf LV, Yang Y, Wang J, Xie Q, Braunger B, Tamm ER, Zavadil J, Cvekl A. (2009). Identification of pax6-dependent gene regulatory networks in the mouse lens. PLoS ONE 4, e4159. (PubMed)

Tamm ER, Ethier CR. (2009). Current aspects of aqueous humor dynamics and glaucoma. Exp. Eye Res. 88. 618-9. (PubMed)

Tamm ER (2009). The trabecular meshwork outflow pathways: structural and functional aspects. Exp Eye Res. 88, 648-55 (PubMed)

Fuchshofer R, Tamm ER. (2009). Modulation of extracellular matrix turnover in the trabecular meshwork. Exp. Eye Res. 88, 683-8 (PubMed)

Fuchshofer R, Stephan DA, Russell P, Tamm ER. (2009). Gene expression profiling of TGFβ2- and/or BMP7-treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-β2 signaling. Exp. Eye Res. 88, 1020-32 (PubMed)

Junglas B, Yu AHL., Welge-Lüssen U, Tamm ER, Fuchshofer R. (2009). Connective tissue growth factor induces extracellular matrix deposition in human trabecular meshwork cells. Exp. Eye Res. 88, 1065-75 (PubMed)

Davis N, Yoffe C, Raviv S, Antes R, Berger J, Holzmann S, Stoykova A, Overbeek PA, Tamm ER, Ashery-Padan R. (2009). Pax6 dosage requirements in iris and ciliary body differentiation. Dev Biol.; 333(1):132-42. (PubMed)

2008

Tamm ER. (2008). Molecular Approaches to Glaucoma: Intriguing Clues for Pathology. In: Current Topics in Membranes, The Eye’s Aqueous Humor (Ed. Civan M.M.). Elsevier Inc. pp. 379-425.

Tamm ER. (2008). The Functional Role of Myocilin in Glaucoma. In: Ophthalmology Research: Mechanisms of the Glaucomas (Eds. Shields M.B., Tombran-Tink J., Barnstable C.J.). Humana Press, Totowa, NJ, pp. 219-231.

Tamm ER, Kellenberger A. (2008). Aqueous Humor Dynamics and Trabecular Meshwork. In: Eye, Retina, and Visual System of the Mouse. III Organization of the Adult Mouse Eye and Central Visual System (Eds. Chalupa L.M., Williams R.W.). MIT Press, p. 129-33.

Paper W, Kroeber M, Heersink S, Stephan DA, Fuchshofer R, Russell P, Tamm ER. (2008). Elevated amounts of myocilin in the aqueous humor of transgenic mice cause significant changes in ocular gene expression. Exp. Eye Res. 87:257-67. (PubMed)

Wurm A, Sock E, Fuchshofer R, Wegner M, Tamm ER. (2008). Anterior segment dysgenesis in the eyes of mice deficient for the high-mobility-group transcription factor Sox11. Exp. Eye Res., 86:895-907. (PubMed)

Janssen A, Hoellenriegel J, Fogarasi M, Schrewe H, Seeliger M, Tamm ER, Ohlmann A, May CA, Weber BH, St?hr H. (2008). Abnormal vessel formation in the choroid of mice lacking tissue inhibitor of metalloprotease-3. Invest. Ophthalmol. Vis. Sci.; 49:2812-22. (PubMed)

2007

Tamm ER, Fuchshofer R. What Increases Outflow Resistance in Primary Open-angle Glaucoma? Surv Ophthalmol. 2007 Nov;52(6 Suppl):S101-4. (PubMed)

Pirity MK, Wang WL, Wolf LV, Tamm ER, Schreiber-Agus N, Cvekl A. Rybp, a polycomb complex-associated protein, is required for mouse eye development. BMC Dev Biol.; 7:39. (PubMed)

Fuchshofer R, Yu AH, Welge-Lussen U, Tamm ER. (2007) Bone morphogenetic protein-7 is an antagonist of transforming growth factor-beta2 in human trabecular meshwork cells. Invest Ophthalmol Vis Sci.; 48(2):715-26. (PubMed)

2006

Russell P, Walsh E, Chen W, Goldwich A, Tamm ER. (2006) The effect of temperature on gene silencing by siRNAs: implications for silencing in the anterior chamber of the eye. Exp Eye Res.; 82(6):1011-6. (PubMed)

Kroeber M, Ohlmann A, Russell P, Tamm ER. (2006) Transgenic studies on the role of optineurin in the mouse eye. Exp Eye Res.; 82(6):1075-85. (PubMed)

2005

Hinz B, Rosch S, Ramer R, Tamm ER. (2005) Brune K. Latanoprost induces matrix metalloproteinase-1 expression in human nonpigmented ciliary epithelial cells through a cyclooxygenase-2-dependent mechanism. FASEB J.; 19(13):1929-31. (PubMed)

Ricard CS, Tamm ER. (2005) Focus on Molecules: Myocilin/TIGR. Exp Eye Res.; 81(5):501-2. (PubMed)

Davis-Silberman N, Kalich T, Oron-Karni V, Marquardt T, Kroeber M, Tamm ER,
Ashery-Padan R. (2005) Genetic dissection of Pax6 dosage requirements in the developing mouse eye. Hum Mol Genet.; 14(15):2265-76. (PubMed)

Gottanka J, Kirch W, Tamm ER. (2005) The origin of extrinsic nitrergic axons supplying the human eye. J Anat.; 206(3):225-9. (PubMed)

Ohlmann A, Scholz M, Goldwich A, Chauhan BK, Hudl K, Ohlmann AV, Zrenner E, Berger W, Cvekl A, Seeliger MW, Tamm ER. (2005). Ectopic norrin induces growth of ocular capillaries and restores normal retinal angiogenesis in Norrie disease mutant mice. J. Neurosci.; 25, 1701-1710. (PubMed)

Friedrich RP, Schlierf B, Tamm ER, Bosl MR, Wegner M. (2005) The class III POU domain protein Brn-1 can fully replace the related Oct-6 during Schwann cell development and myelination. Mol. Cell. Biol. 25, 1821-9. (PubMed)

Zillig M, Wurm A, Grehn FJ, Russell P, Tamm ER. (2005) Overexpression and properties of wild-type and Tyr437 His mutated myocilin in the eyes of transgenic mice. Invest. Ophthalmol. Vis. Sci. 46, 223-34. (PubMed)

Goldwich A, Baulmann DC, Ohlmann A, Flügel-Koch C, Sch?cklmann H, Tamm ER. (2005). Myocilin is expressed in the glomerulus of the kidney and induced in mesangioproliferative glomerulonephritis. Kidney Int., 67, 140-151. (PubMed)

2004

Tamm ER, Carassa RG, Albert DM, Gabelt BT, Patel S, Rasmussen CA, Kaufman PL. (2004). Viscocanalostomy in rhesus monkeys. Arch. Ophthalmol., 122, 1826-1838. (PubMed)

Flügel-Koch C, Ohlmann A, Fuchshofer R, Welge-Lüssen U, Tamm ER. (2004). Thrombospondin-1 in the trabecular meshwork: localization in normal and glaucomatous eyes, and induction by TGF-beta1 and dexamethasone in vitro. Exp. Eye Res., 79, 649-663. (PubMed)

Sock E, Rettig SD, Enderich J, Bosl MR, Tamm ER, Wegner M. (2004) Gene targeting reveals a widespread role for the high-mobility-group transcription factor Sox11 in tissue remodeling. Mol. Cell Biol., 24, 6635-6644. (PubMed)

Cvekl A, Tamm ER. (2004). Anterior eye development and ocular mesenchyme: New insights from mouse models and human diseases. Bioessays, 26, 378-386. (PubMed)

Knaupp, C, Flügel-Koch C, Goldwich A, Ohlmann, A, Tamm ER. (2004) The expression of myocilin during murine eye development. Graefe’s Arch. Clin. Exp. Ophthalmol., 242, 339-45 . (PubMed)

2003

Santas AJ, Bahler C, Peterson JA, Filla MS, Kaufman PL, Tamm ER, Johnson D, Peters DP. (2003). The heparin II domain of fibronectin modulates aqueous outflow in cultured anterior segments of human eyes. Invest. Ophthalmol. Vis. Sci., 44, 4796-4804. (PubMed)

Rhee, DJ, Tamm, ER, and Russell, P. (2003) Donor corneoscleral buttons: A new source of trabecular meshwork for research. Exp. Eye Res., 77, 749-756. (PubMed)

Ohlmann A, Goldwich A, Flügel-Koch C, Fuchs AV, Schwager K, Tamm ER. (2003) The secreted glycoprotein myocilin is a component of the myelin sheath in peripheral nerves. Glia, 43, 128-140. (PubMed)

Goldwich A, Ethier CR, Chan DW-H, Tamm ER. (2003). Perfusion with the olfactomedin domain of myocilin does not affect outflow facility. Invest. Opthalmol. Vis. Sci., 44, 1953-1961. (PubMed)

2002

Baulmann D, Ohlmann A, Flügel-Koch C, Goswami S, Cvekl A, Tamm ER. (2002). Pax6 heterozygous eyes show defects in chamber angle differentiation that are associated with a wide spectrum of other anterior eye segment abnormalities. Mech. Develop. 118, 3-17. (PubMed)

Flügel-Koch C, Ohlmann A, Piatigorsky J, Tamm ER. (2002). Disruption of anterior segment development by TGF-beta1 overexpression in the eyes of transgenic mice. Dev. Dyn. 225, 111-125. (PubMed)

Weber BHW, Schrewe H, Molday LL, Gehrig A, White KL, Seeliger MW, Jaissle GB, Friedburg C, Tamm ER, Molday RS. (2002). Inactivation of the murine X-linked juvenile retinoschisis gene, rs1h, suggests a role of retinoschisin in retinal cell layer organization and synaptic structure. PNAS, 99, 6222-6227. (PubMed)

Rao V, Wawrousek E, Tamm ER, Zigler S. Jr. (2002). Rho GTPase inactivation impairs lens growth and integrity. Lab. Invest. 82, 231-239. (PubMed)

Borrás T, Rowlette LLS, Tamm ER, Gottanka J, Epstein DL. (2002) Effects of elevated intraocular pressure on outflow facility and TIGR/MYOC expression in perfused human anterior segments. Invest. Ophthalmol. Vis. Sci. 43, 33-40. (PubMed)

Tamm ER. (2002) Myocilin and glaucoma. Facts and ideas. Prog. Ret. Eye Res. 21, 395-428. (PubMed)

Ohlmann A, Tamm ER. (2002)? Die Rolle von Myocilin bei der Pathogenese des prim?ren Offenwinkelglaukoms. Der Ophthalmologe, 99, 672-677. (Springer)

2001

Tamm ER, Polansky J. (2001). The TIGR/MYOC gene and glaucoma: opportunities for new understandings. J. Glaucoma, 10(Suppl 1), S9-S12. (PubMed)

Brady JP, Garland DL, Green DE, Tamm ER, Giblin F, Wawrousek EF. (2001). aB-Crystallin is not essential for development of a transparent lens but may be critical for muscle integrity. Invest. Ophthalmol. Vis. Sci., 42, 2924-2932. (PubMed)

Maih?fner C, Schl?tzer-Schrehardt U, Gühring H, Zeilhofer HU, Naumann GOH, Tamm ER, Brune K. (2001). Specific loss of ciliary COX-2 expression in patients with primary open-angle glaucoma. Invest. Ophthalmol. Vis. Sci., 42, 2616-2624.

Russell P, Tamm ER, Grehn FJ, Picht G, Johnson M. (2001). The presence and properties of myocilin in the aqueous humor. Invest. Ophthalmol. Vis. Sci., 42, 983-986. (PubMed)

Tamm ER, Russell, P. (2001) The Role of Myocilin/TIGR in Glaucoma. Results of the Glaucoma Research Foundation Catalyst Meeting in Berkeley, CA, March 2000. J. Glaucoma, 10, 329-339. (PubMed)

2000

Piatigorsky J, Kozmik Z, Horwitz J, Ding L, Carosa E, Robison WG.Jr., Steinbach PJ, Tamm ER. (2000). Omega-crystallin of the scallop lens. A dimeric aldehyde dehydogenase class 1/2 enzyme-crystallin. J. Biol. Chem. 275, 41064-41073. (PubMed)

Kirstein L. Cvekl A, Chauhan BK, Tamm ER. (2000). Regulation of human myocilin/TIGR gene transcripton in trabecular meshwork cells and astrocytes: Role of upstream stimulatory factor. Genes Cells, 5, 661-676. (PubMed)

Karali A, Russell P, Stefani FH, Tamm ER. (2000). Localization of myocilin/ trabecular meshwork inducible glucocorticoid response protein in the human eye. Invest. Opthalmol. Vis. Sci., 41, 729-740. (PubMed)

Publications

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Lehrstuhl für Humananatomie und Embryologie