Prof. Dr. Thomas Jaki

Confidence Intervals for Adaptive Trial Designs II: Case Study and Practical Guidance. (externer Link, ?ffnet neues Fenster)

Robertson, David S., Burnett, Thomas, Choodari‐Oskooei, Babak, Dimairo, Munya,Grayling, Michael, Pallmann, Philip und Jaki, Thomas (2025)

Seamless monotherapy-combination phase I dose-escalation model-based design. (externer Link, ?ffnet neues Fenster)

Daniells, Libby , Jaki, Thomas , Dayimu, Alimu , Demiris, Nikos, Bristi, Basu, Symeonides, Stefan  und Mozgunov, Pavel (2025)

Incorporating historic information to further improve power when conducting Bayesian information borrowing in basket trials. (externer Link, ?ffnet neues Fenster)

Daniells, Libby, Mozgunov, Pavel, Barnett, Helen, Bedding, Alun und Jaki, Thomas (2025)

How to add baskets to an ongoing basket trial with information borrowing. (externer Link, ?ffnet neues Fenster)

Daniells, Libby , Mozgunov, Pavel , Barnett, Helen, Bedding, Alun und Jaki, Thomas (2025)

Personalized predictions to identify individuals most likely to achieve 10% weight loss with a lifestyle intervention. (externer Link, ?ffnet neues Fenster)

Kuhlemeier, Alena , Van Horn, David J., Jaki, Thomas , Wilson, Dawn K., Resnicow, Ken , Jimenez, Elizabeth Y. und Van Horn, M. Lee (2025)

A Preplanned Multi‐Stage Platform Trial for Discovering Multiple Superior Treatments With Control of FWER and Power. (externer Link, ?ffnet neues Fenster)

Greenstreet, Peter, Jaki, Thomas , Bedding, Alun und Mozgunov, Pavel (2024)

Adaptive enrichment trial designs using joint modelling of longitudinal and time-to-event data. (externer Link, ?ffnet neues Fenster)

Burdon, Abigail J., Baird, Richard D. und Jaki, Thomas  (2024)

A seamless Phase I/II platform design with a time-to-event efficacy endpoint for potential COVID-19 therapies. (externer Link, ?ffnet neues Fenster)

Jaki, Thomas , Barnett, Helen, Titman, Andrew und Mozgunov, Pavel (2024)

Group sequential designs for clinical trials when the maximum sample size is uncertain. (externer Link, ?ffnet neues Fenster)

Yarahmadi, Amin, Dodd, Lori E., Jaki, Thomas , Horby, Peter und Stallard, Nigel (2024)

Validation of predicted individual treatment effects in out of sample respondents. (externer Link, ?ffnet neues Fenster)

Kuhlemeier, Alena, Jaki, Thomas , Witkiewitz, Katie, Stuart, Elizabeth A. und Van Horn, M. Lee (2024)

A multi‐arm multi‐stage platform design that allows preplanned addition of arms while still controlling the family‐wise error. (externer Link, ?ffnet neues Fenster)

Greenstreet, Peter, Jaki, Thomas , Bedding, Alun, Harbron, Chris und Mozgunov, Pavel (2024)

Adding experimental treatment arms to multi‐arm multi‐stage platform trials in progress. (externer Link, ?ffnet neues Fenster)

Burnett, Thomas, K?nig, Franz und Jaki, Thomas  (2024)

Joint TITE-CRM: A Design for Dose Finding Studies for Therapies with Late-Onset Safety and Activity Outcomes. (externer Link, ?ffnet neues Fenster)

Barnett, Helen, Boix, Oliver, Kontos, Dimitris und Jaki, Thomas  (2024)

A comparison of model-free phase I dose escalation designs for dual-agent combination therapies. (externer Link, ?ffnet neues Fenster)

Barnett, Helen, George, Matthew, Skanji, Donia, Saint-Hilary, Gaelle, Jaki, Thomas  und Mozgunov, Pavel (2024)

Predicting Individual Treatment Effects: Challenges and Opportunities for Machine Learning and Artificial Intelligence. (externer Link, ?ffnet neues Fenster)

Jaki, Thomas , Chang, Chi, Kuhlemeier, Alena und Van Horn, M. Lee (2024)

Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (externer Link, ?ffnet neues Fenster)

Yap, Christina , Solovyeva, Olga , de Bono, Johann , Rekowski, Jan , Patel, Dhrusti , Jaki, Thomas , Mander, Adrian , Evans, Thomas R Jeffry, Peck, Richard, Hayward, Kathryn S , Hopewell, Sally, Ursino, Moreno, Rantell, Khadija Rerhou, Calvert, Melanie, Lee, Shing, Kightley, Andrew, Ashby, Deborah, Chan, An-Wen, Garrett-Mayer, Elizabeth, Isaacs, John D, Golub, Robert, Kholmanskikh, Olga, Richards, Dawn, Boix, Oliver, Matcham, James, Seymour, Lesley, Ivy, S Percy, Marshall, Lynley V, Hommais, Antoine, Liu, Rong, Tanaka, Yoshiya, Berlin, Jordan, Espinasse, Aude, Dimairo, Munyaradzi  und Weir, Christopher J (2023)

Medicines and Healthcare products Regulatory Agency’s “Consultation on proposals for legislative changes for clinical trials”: a response from the Trials Methodology Research Partnership Adaptive Designs Working Group, with a focus on data sharing. (externer Link, ?ffnet neues Fenster)

Law, Martin, Couturier, Dominique-Laurent, Choodari-Oskooei, Babak, Crout, Phillip, Gamble, Carrol, Jacko, Peter, Pallmann, Philip, Pilling, Mark, Robertson, David S., Robling, Michael, Sydes, Matthew R., Villar, Sofía S., Wason, James, Wheeler, Graham, Williamson, S. Faye, Yap, Christina und Jaki, Thomas  (2023)

Reducing intrusive memories after trauma via an imagery-competing task intervention in COVID-19 intensive care staff: a randomised controlled trial (externer Link, ?ffnet neues Fenster).

Iyadurai, Lalitha, Highfield, Julie, Kanstrup, Marie, Markham, Alfred, Ramineni, Varsha, Guo, Boliang, Jaki, Thomas , Kingslake, Jonathan, Goodwin, Guy M., Summers, Charlotte, Bonsall, Michael B. und Holmes, Emily A. (2023)

Determining the minimum duration of treatment in tuberculosis: An order restricted non‐inferiority trial design. (externer Link, ?ffnet neues Fenster)

Serra, Alessandra , Mozgunov, Pavel, Davies, Geraint und Jaki, Thomas (2023)

Development of consensus-driven SPIRIT and CONSORT extensions for early phase dose-finding trials: the DEFINE study. (externer Link, ?ffnet neues Fenster)

Solovyeva, Olga , Dimairo, Munyaradzi , Weir, Christopher J. , Hee, Siew Wan , Espinasse, Aude, Ursino, Moreno, Patel, Dhrusti , Kightley, Andrew, Hughes, Sarah, Jaki, Thomas , Mander, Adrian, Evans, Thomas R. Jeffry, Lee, Shing, Hopewell, Sally, Rantell, Khadija Rerhou, Chan, An-Wen, Bedding, Alun, Stephens, Richard, Richards, Dawn, Roberts, Lesley, Kirkpatrick, John, de Bono, Johann  und Yap, Christina  (2023)

Exploring the issues that influence how people with rare neurological conditions engage in physical activity. (externer Link, ?ffnet neues Fenster)

Buscemi, Valentina, Boaz, Annette, Dawes, Helen, Jaki, Thomas , Jones, Fiona, Marsden, Jonathan, Paul, Lorna, Playle, Rebecca, Randell, Elizabeth, Robling, Michael, Rochester, Lynn, Busse, Monica und Ramdharry, Gita (2023)

Early phase clinical trials in oncology: Realising the potential of seamless designs (externer Link, ?ffnet neues Fenster)

Jaki, Thomas , Burdon, Abigail , Chen, Xijin , Mozgunov, Pavel, Zheng, Haiyan  und Baird, Richard  (2023)

A Bayesian multi‐arm multi‐stage clinical trial design incorporating information about treatment ordering. (externer Link, ?ffnet neues Fenster)

Serra, Alessandra , Mozgunov, Pavel und Jaki, Thomas  (2023)

Treating intrusive memories after trauma in healthcare workers: a Bayesian adaptive randomised trial developing an imagery-competing task intervention. (externer Link, ?ffnet neues Fenster)

Ramineni, Varsha , Millroth, Philip, Iyadurai, Lalitha, Jaki, Thomas , Kingslake, Jonathan , Highfield, Julie, Summers, Charlotte , Bonsall, Michael B. und Holmes, Emily A.  (2023)

Point estimation for adaptive trial designs II: Practical considerations and guidance. (externer Link, ?ffnet neues Fenster)

Robertson, David S., Choodari‐Oskooei, Babak, Dimairo, Munya , Flight, Laura, Pallmann, Philip  und Jaki, Thomas  (2023)

Online error rate control for platform trials. (externer Link, ?ffnet neues Fenster)

Robertson, David S., Wason, James M. S. , K?nig, Franz, Posch, Martin  und Jaki, Thomas  (2023)

Backfilling cohorts in phase I dose-escalation studies (externer Link, ?ffnet neues Fenster)

Barnett, Helen, Boix, Oliver, Kontos, Dimitris und Jaki, Thomas  (2023)

Updating the probability of study success for combination therapies using related combination study data. (externer Link, ?ffnet neues Fenster)

Graham, Emily , Harbron, Chris und Jaki, Thomas  (2023)

A comparison of Bayesian information borrowing methods in basket trials and a novel proposal of modified exchangeability‐nonexchangeability method. (externer Link, ?ffnet neues Fenster)

Daniells, Libby , Mozgunov, Pavel, Bedding, Alun und Jaki, Thomas  (2023)