Profile
Profile
Education and Academic Career???? Prof. Dr. Inga Neumann
| ?Since 2001: | Full professor of Neurobiology & Animal Physiology, Chair of Department of Behavioural & Molecular Neurobiology, University of Regensburg, Germany |
| ?1994-2001: | Senior scientist, Max-Planck-Institute of Psychiatry, Munich, Germany, Behavioural Neuroendocrinology Group |
| ?1996: | Habilitation and venia legendi, Ludwig-Maximilians-University, Munich, Germany |
| ?1992-1994: | ?Postdoctoral student, University of Calgary, Canada, lab Prof. Q. Pittman, PhD |
| ?1992: | PhD in Neurobiology, Dept. of Cell Biology, University of Leipzig, East Germany |
| ?1987-1992: | Scientific assistant (PhD student), Karl-Marx-University of Leipzig, Leipzig |
| ?1987: | Diploma in Biology, Neurobiology, Karl-Marx-University of Leipzig |
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FELLOWSHIPS AND AWARDS
| ?2019: | ?ECNP European Neuropsychopharmacology Award, Kopenhagen |
| ?1997-2001: | ?Heisenberg stipend of the Deutsche Forschungsgemeinschaft |
| ?1994: | ?postdoctoral stipend of the Alberta Heritage Foundation, Canada, 6 months |
| ?1992-94: | ?postdoctoral stipend of the Human Frontier Science Program (HFSPO) |
| ?1992: | ?Award for best PhD thesis, University of Leipzig |
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Academic Services
| 2017-2026: | Director of the DFG Graduate School "Neurobiology of Emotion Dysfunctions" (GRK 2174) at University of Regensburg |
| 2006 -2016: | Organizer & Director of the International Elite-Master-Programme “Experimental and Clinical Neurosciences” at University of Regensburg |
| 10/2017 – 09/2019: | Dean of the Faculty of Biology and Preclinical Medicine, Uni Regensburg |
| 2015-2017: | Vice Dean of the Faculty of Biology and Preclinical Medicine |
| 2013-2015: | Dean for Research, Faculty of Biology and Preclinical Medicine |
| 2012-2016: | Vice Women’s representative of the University of Regensburg |
| Since 2010: | Co-Chair of the Research Initiative “Aggression and Violence in Culture and Nature”; Establishment & Co-Director of the interdisciplinary Master-Programme “Criminology and Aggression Research” at Uni Regensburg |
ORGANISATION OF SCIENTIFIC MEETINGS
| ?2019: | ?Organizer German-Israel MINERVA School “Neurobiology of Socio-Emotional Behaviour” |
| ?2015: | ?Chair of the 1st German Neuropeptide Conference, Regensburg |
| ?2013: | ?Chair of the International Parental Brain Conference, Regensburg |
| ?2007: | ?Chair, 7th World Congress on Neurohypophysial Hormones (WCNH), Regensburg |
Grants
Grants
| 2023 - 2026: | DFG 465/33-2 "Bedeutung des Translokator Proteins (18kDa) (TSPO) als diagnostische und therapeutische Zielstruktur im Nervensystem“ |
| 2022 - 2025: ?? | DFG 462/37 "Die Bedeutung der durch chronische Oxytocin-Gabe induzierten alternativen Splice-Variante des CRF Rezeptor CRFR2α" |
| 2021 - 2024: ? ? ? ? ? ? ? ?? ?? ??????????? | DFG Ne 465/36 “Die Rolle von Endocanabinoiden in der Regulation von sozialer Angst“ |
| 2019 - 2022: | DFG Ne 465/34 “Neuronale Mechanismen der sozialen Angstkonditionierung in der Maus“ |
| 2019 – 2022: | DFG Ne465/33 ?Bedeutung des Translokator-Proteins 18kDa TSPO als diagnostische und therapeutische Zielstruktur im Nervensystem“ |
| 2018 – 2021: | DFG Ne 465/31 “Effects of acute and chronic oxytocin activation on intraneuronal signaling cascades” |
| 2017 – 2021: | DFG Graduate programme “Neurobiology of Emotion Dysfunctions” (GRK 2174) - prolongation until 2026 |
| 2014-2018: | DFG Ne 465/27-1 (1 PhD, 1 technician + 64.000) � “Chronic oxytocin and NPS administration” |
| 2015-2018: | BMBF-Verbund (Joint research project) “OptiMD” within research network for mental diseases: Identification and Validation of new target structures of the brain for anti-depressive medication in animal models” (SP1) |
| 2013-2018: | 7th FP EU; FemNat CD (Neurobiology of female conduct disorder; 315.000 �) |
| 2006 – 2016: | Elitenetwork Bavaria: Elite Masterprogramme “Experimental and Clinical Neuroscience” |
| 2012-2016: | DFG Ne 465/16-2 (1 PhD, 1 technician + 89.000 �) “Effects of chronic stress in pregnancy on hypothalamic gene expression patterns” |
| 2011-2014: | DFG (1 postdoc + 75.000) “Intracellular actions of oxytocin: link to anxiolysis” |
| 2008-2011/15: | DFG (1TA, 1PhD student + 76.000 �), “Stress adaptations in pregnancy” |
| 2006-2012: | DFG (1TA, 2 PhD, + 85.000�), “Chronic stress and colitis” |
| 2009-2012: | DFG (1 postdoc, 1 PhD + 63.000 �), “Neurobiology of aggression” |
| 2008-2011: | BMBF-Verbund (Joint research project) “Oxytocin and social behaviour” |
| 2008-2011: | Bavarian Research Foundation (68.000 �) “Sexual activity and anxiolysis” |
| 2010-2012: | Bavarian Research Foundation (72.000 �) “Oxytocin actions in social fear conditioning” |
| 2013-2015: | Bavarian Research Foundation (72.000 �) “Epigenetic mechanisms of oxytocin actions in fear conditioning” |
| 2001-2007: | Volkswagenstiftung (473.000 �), “Prenatal stress, anxiety and neurogenesis” |
| DAAD - SFN: | With Prof. Larry Young, Emory University, Atlanta, 2004-2006 |
| DAAD - UK: | With Prof. John Russell, University of Edinburgh, 2008-2010 |
| DAAD - Australia: | With Prof. Iain McGregor, University of Sydney, 2011-2013 |
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Publications
Publications
List of publications 2006-2024 ???????????????????????????????????????? Prof. Dr. Inga D. Neumann
(1)?? Peer-reviewed papers
2024
Grossmann CP, Sommer C, Fahliogullari IF, Neumann ID, Menon R. Mating-induced release of oxytocin in the mouse lateral septum: Implications for soical fear extinction: Psychoneuroendocrinology 2024;166:107083.doi:10.1016/j.psyneuen.2024.107083.
2023
Neumann ID, Menon R. Detection, processing, and reinforcement of social cues: regulation by the oxytocin system. Nat Rev Neurosci. 2023;doi:10.1038/s41583-023-00759-w. Online ahead of print
Neumann ID. Monitoring oxytocin signaling in the brain: more than a love story. Compr. Psychoneuroendocrinology 2023;(16)100206.??
Pandamooz S, Salehi MS, Jurek B, Meinung CP, Azarpira N, Dianatpour M, Neumann ID.Oxytocin Receptor Expression in Hair Follicle Stem Cells: A Promising Model for Biological and Therapeutic Discovery in Neuropsychiatric Disorders. Stem Cell Rev Rep 2023;doi: 10.1007/s12015-023-10603-4. Online ahead of print.
Tabak BA, Leng G, Parker KJ, Verbarlis JG, Ziegler TE, Lee MR, Neumann ID, Mende AJ. Advances in human oxytocin measurement: challenges and proposed solutions. Mol Psych 2023;28(1):127-140. ????
Bludau A, Neumann ID, Menon R. HDAC1-mediated regulation of GABA signaling within the lateral septum facilitates long-lasting social fear extinction in male mice. Transl Psychiatry 2023;13:10 ; https://doi.org/10.1038/s41398-023-02310-y.
Gryksa K, Schmidtner AK, Masís-Calvo M, Rodríguez-Villagra OA, Havasi A, Wirobski G, Maloumby R, J?gle H, Bosch OJ, Slattery DA, Neumann ID. Selective breeding of rats for high (HAB) and low (LAB) anxiety-related behaviour: A unique model for comorbid depression and social dysfunctions. Neurosci Biobehav Rev 2023;152:105292. doi: 10.1016/j.neubiorev.2023.105292.
2022
Oliveira VEM, de Jong TR, Neumann ID. Syntetic Oxytocin and Vasopressin act within the central Amygdala to exacerbate agression in female wistar rats. Front Neurosci 2022;16:906617.
Leschik J, Gentile A, Cicek C, Péron S, Tevosian M, Beer A, Radyushkin K, Bludau A, Ebner K, Neumann ID, Singewald N, Berninger B, Lessmann V, Lutz B. Brain-derived neurotrophic factor expression in serotonergic neurons improves stress resilience and promotes adult hippocampal neurogenesis. Prog Neurobiol 2022;217:102333.
Cohen AJ, Neumann ID. A model for the social neurscience of music productions begins on a dubious note: Commentary on Greenberg et al. Am Psychol 2022;(4)616-18.
Rupprecht R, Wetzel CH, Dorostkar M, Herms J, Albert NL, Schwarzbach J, Schumacher M, Neumann ID. Translocator protein (18kDa) TSPO: a new diagnostic or therapeutic target for stress-related disorders? Review Mol Psychiatry 2022;27(7):2918-2926.
Royer M, Pai B, Menon R, Bludau A, Gryksa K, Perry RB, Ulitsky I, Meister G, Neumann ID. Transcriptome and chromatin alterations in social fear indicate association of MEG3 with successful fear extinction. Mol Psych 2022;27(10): 4064–4076.
Meyer M, Jurek B, Alfonso-Prieto M, Ribeiro R, Milenkovic VM, Winter J, Hoffmann P, Wetzel CH, Giorgetti A, Carloni P, Neumann ID. Structure-function relationships of the disease-linked A218T oxytocin receptor variant. Mol Psychiatry 2022; 27(2);907-917.
Gryksa K, Neumann ID. Consequences of pandemic-associated social restrictions: Role of social support and the oxytocin system. Psychoneuroendocrinology 2022;135:105601.
Carboni L, El Khoury A, Beiderbeck DI, Neumann ID, Mathé AA. Neuropeptide Y, calcitonin gene-related peptide, and neurokinin A in brain regions of HAB rats correlate with anxiety-like behaviours. Eur Neuropsychopharmacol 2022;7;57:1-14.
Menon R, Suess T, Oliveira VEM, Neumann ID, Bludau A. Neurobiology of the lateral septum: regulation of social behavior. Trends Neurosci 2022; 45(1):27-40.
2021
Winter J, Meyer M, Berger I, Royer M, Bianchi M, M. Sc., Kuffner K, Peters S, Stang S, Langgartner D, Hartmann F, Schmidtner AK, Reber SO, Bosch OJ, Bludau A, Slattery DA, van den Burg E, Jurek B, Neumann ID (2021). Chronic oxytocin-driven alternative splicing of CRFR2α induces anxiety. Mol Psychiatry 2021;?doi:10.1038/s41380-021-01141-x. ??
Oliveira VEM, Lukas M, Wolf HN, Durante E, Lorenz A, Mayer AL, Bludau A, Bosch O, Grinevich V, Egger V, de Jong TR, Neumann ?ID (2021) Oxytocin and vasopressin within the ventral and dorsal lateral septum modulate aggression in female rats. Nat Commun 2021;12(1):2900.
Albantakisa L, Brandia ML, Brückl T, Gebert D, Auer MK, Kopczak A, Stalla GK, Neumann ID, Schilbach L. Oxytocin and cortisol concentrations in adults with and without autismspectrum disorder in response to physical exercise. Psychoneuroendocrinology 2021;(5)100027.
2020
Malik VA, Zajicek F,? Mittmann LA, Klaus J, Unterseer S, Rajkumar S, Pütz B, Deussing JM, Neumann ID, Rupprecht R, Di Benedetto B. GDF15 promotes simultaneous astrocyte remodeling and tight junction strengthening at the blood-brain barrier. J Neurosci Res.;doi: 10.1002/jnr.24611
Tang Y, Benusiglio D, Lefevre A, Hilfiger L, Althammer F, Bludau A, Hagiwara D, Baudon A, Schimmer J, Kirchner MK, Roy RK, WangvS, Eliava M, Wagner S, Conzelmann KK, Schwarz M, Stern JE, Leng G, Charlet A, Grinevich V, Neumann ID. Social touch promotes inter-female communication via oxytocin parvocellular neurons. Nat Neurosci 2020;(9):1125-1137.
Grinevich V, Neumann ID. Brain oxytocin: how puzzle stones from animal studies translate into psychiatry. Mol Psychiatry 2020;1-15.
Meyer M, Kuffner K, Winter J, Neumann ID, Wetzel CH, Jurek B. Myocyte Enhancer Factor 2A (MEF2A) Defines Oxytocin-Induced Morphological Effects and Regulates Mitochondrial Function in Neurons. Int J Mol Sci. 2020;21(6):2200.
Anpilov S, Shemesh Y, Eren N, Harony-Nicolas H, Benjamin A, Dine J, Oliveira VEM, Forkosh O, Karamihalev S, Hüttl RE, Feldman N, Berger R, Dagan A , Chen G, Neumann ID, Wagner S, Yizhar O, Chen A. Wireless Optogenetic Stimulation of Oxytocin Neurons in a Semi-natural Setup Dynamically Elevates Both Pro-social and Agonistic Behaviors. Neuron. 2020;107(4):644-655.e7.
Zoicas I, Mühle C, Schmidtner AK, Gulbins E, Neumann ID, Kornhuber J. Anxiety and Depression Are Related to Higher Activity of Sphingolipid Metabolizing Enzymes in the Rat Brain. Cells 2020;9(5):E1239.
2019
Schmidtner AK, Slattery DA, Gl?sner J, Hiergeist A, Gryksa K, Malik VA, Hellmann-Regen J, Heuser I, Baghai TC, Gessner A, Rupprecht R, Di Benedetto B, Neumann ID. Minocycline alters behavior, microglia and the gut microbiome in a trait-anxiety-dependent manner. Transl Psychiatry;9(1):223
Martinetz S, Meinung CP, Jurek B, von Schack D, von den Burg EH, Slattery DA, Neumann ID. De Novo protein synthesis mediated by the eukaryotic elongation factor 2 is required for the anxiolytic effect of oxytocin. Biol Psychiatry;85(10):802-11
Grund T, Tang Y, Benusiglio D, Althammer F, Probst S, Oppenl?nder L, Neumann ID, Grinevich V. Chemogentic activation of oxytocin neurons:?Temporal dynamics, hormonal release and behavioral consequences. Psychoneuroendocrinology;106:77-84
Bludau A, Royer M, Meister G, Neumann ID, Menon R. Epigenetic regulation of the social brain. J Neurosci; Review
Neumann ID, Landgraf R. Tracking oxytocin functions in the rodent brain during the last 30 years: From push-pull perfusion to chemogenetic silencing. J Neuroendocrinology;(3)e12695.soi:10.1111/jne.12695
Oliveira VEM, Neumann ID, de Jong TR. Post-weaning isolation exacerbates aggression in both sexes and affects the vasopressin and oxytocin system in a sex-specific manner. Neuropharmacology;doi:10.1016/j.neuropharm.2019.01.019 (epub ahead of print)
Grund T, Neumann ID. Brain neuropeptide S:?Via GPCR activation to a powerful neuromodulator of socio-emotional behaviors. Cell Tissue Res;375(1):123-32
2018
Menon R, Grund T, Zoicas I, Althammer F, Fiedler D, Biermeier V, Bosch OJ, Hiraoka Y, Nishimori K, Eliava M, Grinevich V, Neumann ID. Oxytocin signalling in the lateral septum prevents social fear during lactation. Curr Biol
Jurek B, Neumann ID. The Oxytocin Receptor:?From Intracellular signalling to behavior:?Physiol Rev. 98 (3):1805-08
Masís-Calvo M, Schmidtner AK, de Moura Oliveira VE, Grossmann CP, de Jong TR, Neumann ID. Animal models of social stress: the dark side of social interactions. Stress;21(5)417-32 1-16
Bowen MT, Neumann ID. Mulitdimensional therapeutic potential of targeting the brain oxytocin system for the treatment of substance use disorders. Curr Top Behav Neurosci. 35:269-87
Bernhard A, van der Merwe C, Ackermann K, Martinelli A, Neumann ID, Freitag CM. Adolescent oxytocin response to stress and its behavioral and endocrine correlates. Horm Behav;105:157-65
Grund T, Neumann ID. Brain neuropeptide S:?via GPCR activation to a powerful neuromodulator of socio-emotional behaviors. Cell Tissue Res;43(5):1156-63
Bosch OJ, Pohl TT, Neumann ID, Young LJ. Abandoned prairie vole mothers show normal maternal care but altered emotionality: Potential influence of the brain corticotropin-releasing factor system. Behav Brain Res.; 341:114-121
de Jong TR, Neumann ID. Oxytocin and Aggression. Curr Top Behav Neurosci. 35:175-92
Grund T, Neumann ID. Neuropeptide S Induces Acute Anxiolysis by Phospholipase C-Dependent Signaling within the Medial Amygdala. Neuropsychopharmacology 43(5):1156-63.
2017
Muttenthaler M, Andersson ?, Vetter I, Menon R, Busnelli M, Ragnarsson L, Bergmayr C, Arrowsmith S, Deuis JR, Chiu HS, Palpant NJ, O'Brien M, Smith TJ, Wray S, Neumann ID, Gruber CW, Lewis RJ, Alewood PF.